Tenelin M Extended-Release Tablet 10/750 mg

Adult dose

This medication is typically administered once daily with the evening meal, and the dosage is adjusted gradually to minimize gastrointestinal side effects associated with metformin. The 20/1000 mg extended-release tablet is taken once daily with one tablet. The 10/750 mg or 10/500 mg extended-release tablets are taken once daily with two tablets simultaneously. For patients who cannot achieve adequate blood sugar control with metformin monotherapy, the initial dose of this medication is set to provide teneligliptin 20 mg once daily alongside the current metformin dosing. For patients transitioning from a combination therapy of teneligliptin and metformin, the dosage of this medication can commence based on the existing metformin and teneligliptin dosing. When converting from immediate-release metformin to extended-release formulations, blood sugar control must be closely monitored and dosage adjusted appropriately. When co-administering with sulfonylureas, reducing the sulfonylurea dosage may be considered to decrease the risk of hypoglycemia. The maximum recommended dosage is teneligliptin 20 mg and extended-release metformin 2000 mg per day. The safety and efficacy of this medication have not been specifically evaluated in patients transitioning from other blood glucose-lowering agents. Any changes during the treatment of type 2 diabetes must be cautiously monitored as they can affect blood sugar control. To maintain the extended-release properties, the tablets should be swallowed whole and not be broken, crushed, or chewed.

This medication assists in controlling blood sugar levels. However, it may rarely cause a serious condition known as lactic acidosis, so caution is necessary. It should not be used in patients with poor kidney function, heart disease, or liver dysfunction. Additionally, treatment should be temporarily halted if undergoing surgery or experiencing severe infections, and should be restarted only after kidney function has recovered. The risk of hypoglycemia may increase when this medication is used in conjunction with other blood glucose-lowering agents, so it is important to be aware of symptoms of hypoglycemia. Regular monitoring of liver and kidney function during treatment is crucial, as well as checking vitamin B12 levels. Pregnant women or those who may become pregnant should not take this medication, and it is also not recommended for nursing mothers. The safety of this medication in children has not been established, and dosage adjustment may be necessary for the elderly based on kidney function. In case of overdose, immediate medical attention should be sought. Lastly, this medication should be kept out of the reach of children and should not be transferred to other containers.

Serious side effects

• Hives
• hypoglycemia
• liver dysfunction
• interstitial pneumonia
• similar to Pemphigus
• acute pancreatitis
• chest discomfort
• respiratory distress
• peripheral edema
• generalized edema

Mild side effects

• Constipation
• dizziness
• abdominal distension
• abdominal discomfort
• nausea
• abdominal pain
• bloating
• stomatitis
• gastric polyps
• colon polyps

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. The suitable storage temperature is room temperature between 1 to 30 degrees Celsius. Proper storage maintains the effectiveness of the medication.

Appearance

Yellow oval extended-release film-coated tablet

Package unit

30 tablets/bottle