Tenelo M Extended Release Tablet 10/750 mg

Adult dose

This medication is typically administered once daily with the evening meal, with gradual dosage adjustment to minimize gastrointestinal side effects associated with Metformin. The 20/1000 mg extended-release tablet is taken once daily, one tablet at a time. For those taking the 10/750 mg or 10/500 mg extended-release tablet, the dosage is two tablets once daily, taken simultaneously. In patients who cannot achieve adequate blood sugar control with Metformin monotherapy, the initial dose of this medication should provide Teneligliptin 20 mg once daily along with the current dose of Metformin. In patients switching to this medication from combination therapy with Teneligliptin and Metformin, the dosage can start with the current doses of Teneligliptin and Metformin. When converting from immediate release Metformin to the extended-release preparation, blood sugar control should be closely monitored and appropriate dose adjustments made. When co-administered with sulfonylureas, consideration should be given to reducing the dose of sulfonylureas to decrease the risk of hypoglycemia. The maximum recommended daily doses are Teneligliptin 20 mg and extended-release Metformin 2000 mg. The safety and efficacy of this medication have not been specifically evaluated in patients switching from other hypoglycemic agents. Any change in treatment for patients with type 2 diabetes should be conducted under careful monitoring due to potential changes in blood sugar control. To maintain its extended-release characteristic, this medication should not be crushed, broken, or chewed but should be swallowed whole.

This medication is used to assist with blood sugar control, particularly in patients with diabetes. It contains Metformin, which may be dangerous for patients with impaired kidney function; thus, patients with reduced kidney function should not use it. Additionally, this medication should not be administered to patients with heart failure, acute myocardial infarction, or severe infections. This medication can cause a rare but serious side effect known as lactic acidosis, a condition where lactic acid accumulates in the body and can be life-threatening. Patients at risk of lactic acidosis, such as those with poor liver function or severe hypoxia, should exercise particular caution. Also, taking this medication in conjunction with insulin or sulfonylureas may increase the risk of hypoglycemia, so blood sugar levels must be closely monitored. It is advisable for women who are pregnant, potentially pregnant, or breastfeeding to avoid this medication. During treatment, it is important to avoid alcohol consumption, and if sudden dehydration, severe vomiting, or diarrhea occurs, medical consultation should be sought immediately. If surgery is planned or iodine contrast studies are to be conducted, the medication needs to be temporarily discontinued for a period, and kidney function must be verified before resuming use. Elderly patients or those with compromised kidney function should have regular kidney function tests, and dose adjustments may be necessary. Patients should be well-informed about symptoms of hypoglycemia and initial signs of lactic acidosis, and should seek medical attention immediately if symptoms arise. Some patients may experience side effects such as dyspepsia, constipation, dizziness, skin rashes; any unusual symptoms should be reported to healthcare professionals. There could also be potential interactions with other medications, so it is essential that patients inform their doctor or pharmacist of any other medications they are taking.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash accompanied by high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound weakness, sudden and severe headaches, lightning headaches, seizures, confusion, visual disturbances, paralysis, urine

Mild side effects

• Dizziness
• constipation
• abdominal bloating
• abdominal discomfort
• nausea
• abdominal pain
• flatulence
• stomatitis
• gastric polyps
• colonic polyps

This medication should be stored in a tightly sealed container to prevent air exposure, preferably at room temperature between 1 and 30 degrees Celsius. Storing the medication this way helps maintain its effectiveness and prevents deterioration.

Appearance

Yellow oval-shaped extended release film-coated tablet

Package unit

30 tablets/bottle