Emplom Tablets 5/500 mg

Adult dose

The recommended dosage of this medication is 1 tablet per administration, twice daily. The dosing should be determined based on each patient’s treatment regimen, efficacy, and tolerance, without exceeding a total of 25 mg of empagliflozin and 2000 mg of metformin. For patients receiving metformin alone or in combination with insulin or other drugs, the recommended dose is empagliflozin 5 mg taken twice daily and the patient’s existing metformin dosage. If the patient shows good tolerance and needs additional blood glucose control, the dose of empagliflozin could be increased to 25 mg daily.

This medication can potentially cause a rare but life-threatening condition known as severe lactic acidosis, so caution is required. When used in conjunction with other diabetes medications, hypoglycemia may occur, so blood sugar levels must be monitored closely. It should not be used in patients with moderate to severe renal impairment or in situations suspecting acute kidney injury. In cases of severe infections, dehydration, or serious health conditions such as heart failure, the administration of this medication should be avoided. Prior to and after undergoing examinations using iodine-based contrast agents, this medication should be temporarily discontinued, and should only be resumed after normal kidney function is confirmed. It is advised that this medication not be used by pregnant or potentially pregnant women and nursing mothers. Since this medication is affected by kidney function, regular kidney function testing is necessary, especially for elderly patients or those with reduced kidney function. Caution is necessary for patients at risk of decreased fluid volume, such as those experiencing dehydration, vomiting, or diarrhea when taking this medication. While taking this medication, be vigilant for symptoms of hypoglycemia, and dose adjustments may be necessary when used in combination with insulin or sulfonylureas due to an increased risk of hypoglycemia. Urinary or genital infections may occur, so consult a physician immediately if related symptoms appear. Long-term use may lower vitamin B12 levels, so it is advisable to monitor through blood tests. Alcohol intake can increase the risk of lactic acidosis, so it is important to avoid excessive drinking while on this medication. If food intake is not possible for a prolonged period due to surgery or significant illness, the use of this medication should be temporarily stopped. Immediate treatment should be sought if symptoms of fever, pain or swelling in the genital area, or perineal necrotic symptoms appear, and medication should be discontinued in such cases. This medication is not recommended for children under 18 years, and patients over 75 years should be cautious due to the risk of fluid loss. In the event of an overdose, seek medical attention promptly, as this medication can be removed through hemodialysis.

Serious side effects

Urticaria, severe swelling (edema), difficulty breathing, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in oral/eye mucous membranes, severe skin reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of skin or eyes (jaundice), liver abnormalities, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication should be stored in a tightly sealed container to prevent the entry of air or moisture, and it is recommended to be kept at a room temperature of 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness safely.

Appearance

Biconvex oval film-coated tablets in orange-yellow color

Package unit

10 tablets/box [(10 tablets/PTP)×1], 60 tablets/box [(10 tablets/PTP)×6], 60 tablets/bottle