Pary-M Duo Tablet 5/850 mg

Adult dose

The recommended dosage of this medication is 1 tablet per dose, 2 times a day. Empagliflozin 5 mg 2 times daily (total 10 mg per day) is administered along with the patient's current metformin dosage. If greater blood sugar control is needed, the dose of empagliflozin may be increased to 25 mg (total per day). This medication should be taken with meals to reduce metformin-related gastrointestinal side effects.

This medication may cause a rare side effect known as severe lactic acidosis, thus caution is advised particularly in patients with impaired kidney function or heart disease. There is a risk of hypoglycemia when used with other diabetes medications, so blood sugar levels should be monitored frequently and dosages adjusted as necessary. This medication should not be used in patients with moderate to severe renal impairment or conditions that can cause acute kidney injury. Patients scheduled for surgery or receiving radiocontrast agents should discontinue this medication in advance and resume only after kidney function has returned to normal. Pregnant women, those who may become pregnant, and breastfeeding mothers should not take this medication and should consult a healthcare professional for safety. While on this medication, any occurrence of dehydration, severe infection, or acute heart failure warrants immediate consultation with a physician and potentially discontinuation of the medication. The risk of urinary or genital infections may increase, so prompt treatment is necessary if infection symptoms arise. Vitamin B12 levels may decrease, thus regular blood tests to monitor vitamin B12 status are advisable for long-term use. Elderly patients or those with reduced kidney function should have careful consideration regarding dosage and necessity for use, and regular kidney function monitoring is required. Excessive alcohol should be avoided during the use of this medication, as alcohol consumption can increase the risk of lactic acidosis. Hypoglycemic symptoms may occur, and if dizziness, cold sweat, or confusion appears, blood sugar levels should be checked immediately and appropriate measures taken. This medication can cause fluid loss, particularly in patients who are hypotensive or at risk of dehydration; careful observation of fluid status is essential. Routine monitoring of blood sugar, kidney function, liver function, etc., is crucial to detect any adverse signs early during treatment with this medication. Patients taking this medication should be cautious while driving or operating machinery due to the risk of hypoglycemia or dizziness. In the event of overdose, immediate medical attention is required, especially if symptoms of lactic acidosis are suspected.

Serious side effects

• Hives
• angioedema
• perineal necrosis
• lactic acidosis
• ketoacidosis
• urosepsis and pyelonephritis
• severe edema
• acute kidney injury
• acute cholecystitis
• autoimmune hepatitis

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is recommended to maintain room temperature between 1 to 30 degrees Celsius. Proper storage helps to preserve the effectiveness of the drug for a longer period.

Appearance

Yellowish-white, bilaterally convex, oval film-coated tablet

Package unit

10 tablets/box [10 tablets/PTP X 1], 60 tablets/box [10 tablets/PTP X 6], 60 tablets/bottle