Medication info

Idian Duo Tablet 5/500 mg

Prescription medicationTablet경구
Ingredient · strength
Empagliflozin›5mg / 1 tabletMetformin Hydrochloride›500mg / 1 tablet
Manufacturer / importer
일양약품(주)
Appearance
Orange-yellow, oval, film-coated tablet with convex surfaces
Packaging
10 tablets/box (10 tablets/PTP x 1), 60 tablets/box (10 tablets/PTP x 6), 60 tablets/bottle
Approval status
Active

MFDS item code 202201337 · Approved 2022.04.04

Summary

Main use
Effect in controlling blood sugar for Type 2 diabetes and preventing cardiovascular events
Who takes it
Adults
Adult dose
The recommended dose of this medication is 1 tablet, taken twice daily. The dosage is determined based on the treatment regimen, efficacy, and tolerability for each patient, keeping within the maximum recommended daily dose of empagliflozin 25 mg and metformin 2000 mg. In cases where blood sugar control is insufficient with metformin alone or in combination with other medications, administer empagliflozin 5 mg twice daily. If there is excellent tolerability but additional blood sugar control is needed,

Ingredients

Manufacturer
일양약품(주)

Efficacy & effects

Effect in controlling blood sugar for Type 2 diabetes and preventing cardiovascular events

View approved original text

This medication is used to assist adults with Type 2 diabetes in controlling blood sugar levels in conjunction with dietary and exercise therapy. In particular, it helps manage blood sugar levels effectively by administering empagliflozin and metformin together. It can also be administered to adults with Type 2 diabetes who are not adequately controlled and have cardiovascular disease; caution related to cardiovascular event occurrence should refer to professional information. This medication improves blood sugar management and aids in the treatment of Type 2 diabetes.

How to take

Adult dose

The recommended dose of this medication is 1 tablet, taken twice daily. The dosage is determined based on the treatment regimen, efficacy, and tolerability for each patient, keeping within the maximum recommended daily dose of empagliflozin 25 mg and metformin 2000 mg. In cases where blood sugar control is insufficient with metformin alone or in combination with other medications, administer empagliflozin 5 mg twice daily. If there is excellent tolerability but additional blood sugar control is needed,

Precautions

This medication can cause a rare but very serious condition called lactic acidosis, so you must consult a doctor immediately if any symptoms appear. In addition, there is a risk of hypoglycemia when used together with insulin or sulfonylureas, so caution is needed. This medication should not be used in patients with moderate to severe kidney impairment, acute kidney problems, severe infections, or dehydration. Patients with Type 1 diabetes or those in acute or unstable heart failure should also avoid this medication. Before and after diagnostic tests using radioactive iodine contrast agents, this medication should be temporarily discontinued, and it should be resumed after kidney function has returned to normal. Pregnant or breastfeeding women should not take this medication, and if there is a possibility of pregnancy, they should consult a doctor. Regular kidney function tests should be performed during the use of this medication, especially for the elderly or those with slightly impaired kidney function, as more frequent testing is advisable. In cases with a risk of fluid loss, such as vomiting, diarrhea, or dehydration symptoms, the use of this medication may be temporarily suspended. This medication may cause side effects such as gastrointestinal disturbances, urinary tract infections, genital infections, and increased urination, so report any unusual symptoms to a doctor. Long-term use may lower vitamin B12 levels, so blood tests to check vitamin B12 status are necessary. Alcohol can increase the risk of side effects of this medication, so excessive drinking should be avoided during use. Hypoglycemic symptoms may occur while taking this medication, especially when used along with insulin or other hypoglycemic agents, so blood sugar should be monitored carefully. If food intake is restricted due to surgery or serious illness, this medication should be stopped 48 hours before surgery and resumed after kidney function has returned to normal. This medication is not recommended for children or adolescents under the age of 18, and dosage adjustments are necessary for the elderly based on kidney function. In case of overdose, seek medical attention immediately for appropriate treatment, as serious side effects such as lactic acidosis may occur. Keep this medication out of the reach of children and store it in its original container to maintain its quality.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, abnormal breathing with cough and fever, yellowing of skin or eyes (jaundice), severe lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urine output changes

Mild side effects

  • Hypoglycemia
  • urinary tract infection
  • genital infection
  • increased urination
  • nausea
  • vomiting
  • diarrhea
  • abdominal pain
  • loss of appetite
  • constipation
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  • abnormal liver function tests
  • altered taste
  • itching
  • rash
  • hives
  • erythema
  • increased serum creatinine
  • increased hematocrit
  • decreased vitamin B12 and deficiency
  • decreased fluid volume
  • orthostatic dizziness
  • headache
  • lightheadedness
  • insomnia
  • hypertension
  • anxiety
  • fatigue
  • peripheral edema
  • facial swelling
  • weight loss
  • back pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a tightly closed container to prevent exposure to air or moisture. It is essential to maintain a storage temperature between 1°C and 30°C at room temperature. Proper storage can help maintain the effectiveness of the medication for a longer period.

Appearance and packaging

Appearance

Orange-yellow, oval, film-coated tablet with convex surfaces

Package unit

10 tablets/box (10 tablets/PTP x 1), 60 tablets/box (10 tablets/PTP x 6), 60 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.