Tenesem Extended-Release Tablet 10/500 mg

Adult dose

This medication is generally administered once daily with the evening meal. The 20/1000 mg extended-release tablet is taken once daily as 1 tablet. For patients taking the 10/750 mg or 10/500 mg extended-release tablets, 2 tablets should be taken simultaneously once daily. The initial dosage should include teneligliptin 20 mg once daily and the existing dose of metformin. The maximum recommended daily dose is teneligliptin 20 mg.

This medication is used for the treatment of diabetes and helps regulate blood sugar levels. However, it should not be administered to patients with poor kidney function, heart disease, or liver dysfunction. In particular, patients with acute renal failure, severe infections, or those undergoing surgery should temporarily discontinue this medication. It is also advised that pregnant women or women who could become pregnant, as well as patients with very poor nutritional status, do not use this medication. This medication can rarely cause a serious side effect known as lactic acidosis, which occurs when there is an excessive buildup of lactic acid in the body. Symptoms of lactic acidosis can include vomiting, abdominal pain, muscle pain, and difficulty in breathing; if such symptoms occur, immediate medical attention should be sought. Additionally, this medication can cause hypoglycemia, so blood sugar levels should be carefully monitored in patients taking insulin or other antidiabetic medications. Regular kidney and liver function tests should be conducted while taking this medication, and it is also advisable to check vitamin B12 levels. Alcohol consumption or excessive intake of alcohol can increase the risk of side effects related to this medication and should be avoided. If sudden severe abdominal pain, blisters on the skin, or rashes appear during treatment with this medication, contacting a physician immediately is recommended. Elderly patients may have reduced kidney function, so dosage adjustments and regular monitoring are necessary. This medication has not been established for safety and efficacy in children and should not be used in that population. In case of overdose, immediate medical attention should be sought and, if necessary, dialysis may be performed to remove the drug. This medication should be kept out of reach of children and should not be transferred to other containers.

Serious side effects

Hypoglycemia, lactic acidosis, severe hypoglycemia, bowel obstruction, liver dysfunction, interstitial pneumonia, bullous pemphigoid, acute pancreatitis, hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, severe dermatologic reactions, shortness of breath or difficulty breathing, asthma attacks, cough with fever

Mild side effects

• Dizziness
• constipation
• abdominal distension
• abdominal discomfort
• nausea
• abdominal pain
• bloating
• stomatitis
• gastric polyps
• colon polyps

This medication should be stored in a tightly sealed container that is well-protected from air, and it is best to keep it at room temperature between 1 degree and 30 degrees Celsius. Storing it this way can help maintain the effectiveness of the medication for a longer period.

Appearance

Orange oval-shaped extended-release film-coated tablet

Package unit

30 tablets/bottle