Tenegliptin Extended Release Tablet 10/500 mg

Adult dose

Generally, this medication is administered once daily with the evening meal. The 20/1000 mg extended-release tablet is taken once daily, with 1 tablet per dose. The 10/750 mg or 10/500 mg extended-release tablets are taken once daily with 2 tablets simultaneously. The initial dose provides Tenegliptin 20 mg once daily and the existing dosage of Metformin. The maximum recommended dose is Tenegliptin 20 mg and extended-release Metformin.

This medication is used to treat diabetes and has the effect of lowering blood sugar. However, it can very rarely cause a dangerous condition known as lactic acidosis, so caution is needed. Lactic acidosis is a condition where lactic acid accumulates excessively in the body, which can be life-threatening in severe cases. When taking this medication along with other diabetes treatments, hypoglycemia may occur, so be cautious. It should not be administered to patients with moderately decreased renal function or severe heart disease. Especially when undergoing examinations using radiographic contrast agents, this medication should be discontinued 48 hours prior to the examination and can be resumed only after confirming normal renal function afterward. Women who are pregnant or may become pregnant and patients with severely impaired liver function should not use this medication. During the use of this medication, one should be well aware of hypoglycemia symptoms, and if symptoms occur, immediate action such as consuming sugar is necessary. Additionally, gastrointestinal disturbances, liver function abnormalities, and acute pancreatitis may occur, so if any abnormal symptoms arise, consultation with healthcare personnel is necessary. Elderly patients may experience decreased renal function, so regular renal function tests should be performed, and dosage adjustment may be necessary. In the case of overdose, one should visit a medical institution immediately for appropriate treatment, and blood dialysis may be helpful. It is advisable to avoid alcohol consumption while using this medication, and there may be interactions with other medications, so it is essential to consult with a doctor or pharmacist regarding any medications being taken. Breastfeeding women are also not recommended to take this medication, and if necessary, they should consult healthcare personnel regarding whether to interrupt breastfeeding. Finally, this medication is not used for children as its safety and efficacy have not been established.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, oral/ocular mucous membrane pain, shortness of breath or difficulty breathing, asthma attack, abnormal breathing accompanied by cough+fever, jaundice (yellowing of skin or eyes), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination issues.

Mild side effects

• Hypoglycemia
• constipation
• dizziness
• headache
• weakness
• hunger
• fatigue
• facial swelling
• diarrhea
• indigestion

This medication should be stored in a tightly sealed container to prevent air or moisture from entering and kept at a temperature between 1 to 30 degrees Celsius. By storing it this way, the effectiveness of the medication can be maintained, and degradation can be prevented.

Appearance

Orange oval-shaped extended-release film-coated tablet

Package unit

30 tablets/bottle