Janugreen Duo Tablet 50/1000 mg

Adult dose

This medication is generally taken twice daily with food, and dosage should be gradually increased to reduce gastrointestinal adverse reactions due to metformin. The initial dosage is determined based on the patient's current therapy: 1. For patients not currently receiving metformin: Take 1 tablet of 50/500 mg twice daily, with a possibility to increase to 50/1000 mg. 2. For patients undergoing metformin therapy:

This medication contains sitagliptin and metformin, which are used for diabetes treatment. First, sitagliptin may rarely cause serious allergic reactions, so if symptoms such as skin rash or difficulty breathing occur, the medication must be discontinued immediately and a doctor should be consulted. Also, pancreatitis, which is inflammation of the pancreas, may occur, so if symptoms like abdominal pain, vomiting, or loss of appetite arise, medical personnel should be notified immediately. Metformin may cause a rare complication known as lactic acidosis, which can manifest as muscle pain, difficulty breathing, fatigue, and abdominal pain; in this case, medication use should be stopped immediately and hospitalization is necessary. This medication should not be administered to patients with moderate to severe renal impairment, acute infections, heart failure, or acute myocardial infarction. Additionally, patients scheduled for radiographic contrast studies should stop taking this medication 48 hours prior to the test and resume only after confirming normal renal function. It is not to be used in pregnant or breastfeeding women, or in individuals under 18 years of age. In elderly patients, renal function may decline; thus, dosage adjustments and regular renal function tests are necessary. During treatment with this medication, excessive alcohol consumption should be avoided, and care should be taken for the risk of hypoglycemia during irregular meals or strenuous exercise. Moreover, when combined with other hypoglycemic agents, there may be hypoglycemic symptoms, so attention to symptoms and dosage adjustments may be necessary if needed. Prior to surgery, this medication should be temporarily discontinued and resumed only after confirming normal renal function post-surgery. If severe joint pain or skin vesicles occur during treatment, the doctor should be informed immediately, and medication discontinuation may be necessary in such cases. Regular blood tests and renal function tests are crucial for early detection and management of adverse reactions.

Serious side effects

Hives, angioedema, chest tightness, difficulty breathing, cold sweat, pallor (severe allergic reaction), high fever with severe rash, blisters, skin peeling, oral/ocular mucosal pain (serious skin adverse reactions), difficult or labored breathing, asthma attacks, respiratory abnormalities with cough + fever, jaundice (yellowing of skin or eyes), severe lethargy (liver dysfunction), sudden and severe headache, lightning-like pain

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory tract infections
• nasopharyngitis
• headache
• hypoglycemia
• constipation
• muscle pain

This medication should be stored in a tightly closed container to protect it from air, and it is advisable to keep it at room temperature between 1 to 30 degrees Celsius. By storing it this way, the drug's efficacy can be maintained and degradation can be prevented.

Appearance

Pink oval film-coated tablets

Package unit

30 tablets/box [10 tablets/PTPX3]