Sitagliptin Metformin Tablets 50/500 mg

Adult dose

This medication is generally taken twice daily with food, and the dosage should be increased gradually to minimize gastrointestinal side effects caused by metformin. Initial dosage is determined based on the patient’s current therapy. 1. For patients not currently receiving treatment with metformin: Take this medication 50/500 mg twice daily, 1 tablet each time, and it may be increased to 50/1000 mg twice daily, 1 tablet each time.

This medication is used for diabetes treatment and contains two active ingredients, sitagliptin and metformin. While taking this medication, severe allergic reactions may occur; therefore, if symptoms such as skin rash or respiratory distress appear, discontinue use immediately and consult a physician. Serious side effects have been reported, including acute pancreatitis, which is inflammation of the pancreas, so if symptoms such as abdominal pain or vomiting occur during treatment, notify medical personnel immediately. Patients with severely impaired kidney function, heart failure, or acute myocardial infarction should not use this drug, and it should be discontinued before and after examinations using iodine contrast agents. It is safe for pregnant women or those who might become pregnant, as well as nursing women, not to take this medication. This medication may cause hypoglycemia, so blood glucose levels should be monitored closely, especially when taken with insulin or sulfonylureas. Furthermore, this medication may lead to lactic acidosis, a rare but life-threatening metabolic complication. If sudden symptoms such as respiratory distress, muscle pain, or fatigue occur, notify medical personnel immediately. Regular kidney function and blood tests are recommended during treatment, as vitamin B12 deficiency may occur. Alcohol consumption may increase the risk of side effects from this medication; therefore, excessive drinking should be avoided while on treatment. In cases of undergoing surgery, discontinue use 48 hours prior to the procedure and restart only after confirming normal kidney function. During treatment, regular meals, exercise, and consistent blood glucose testing should be maintained according to the physician's directives.

Serious side effects

Hives, severe swelling (edema), anaphylaxis, angioedema, exfoliative skin conditions (including Stevens-Johnson syndrome), severe rashes or blisters with high fever, skin peeling, oral/ocular mucosal pain, difficulty breathing, dyspnea, pulmonary dysfunction, jaundice, elevated liver enzymes, acute pancreatitis, severe neurological symptoms (such as intense headache, confusion, seizures, etc.), severe edema, acute renal failure, elevated blood pressure, dyspnea, severe complications

Mild side effects

• Diarrhea
• headache
• upper respiratory infection
• nasopharyngitis
• nausea
• vomiting
• abdominal pain
• constipation
• weakness
• muscle pain

Store this medication in a sealed container to prevent the entry of air or moisture, preferably at a temperature between 1 to 30 degrees Celsius. This way, the medication's effectiveness can be well-maintained.

Appearance

Bright pink oval film-coated tablet

Package unit

30 tablets/box [10 tablets/PTPX3]