Sitaglendo Duo Tablet 50/850 mg

Adult dose

This medication is typically taken twice daily with food, and the dosage is increased slowly to reduce gastrointestinal side effects from metformin. 1. For patients not currently treated with metformin: The initial dose is 50/500 mg of this medication, taken twice daily, one tablet at a time, with a potential increase to 50/1000 mg taken twice daily, one tablet at a time. 2. For patients undergoing metformin therapy: Recommended initial dosing...

This medication contains sitagliptin and metformin and is used for diabetes treatment. First, this medication may cause hypersensitivity reactions, so if allergic symptoms such as skin rash, difficulty breathing, or other reactions occur, discontinue use immediately and consult a physician. There is also a risk of serious inflammation of the pancreas called acute pancreatitis; thus, inform medical professionals immediately if symptoms like abdominal pain, vomiting, or nausea occur. This medication should not be administered to patients with severe renal impairment or those with acute heart failure, severe infections, or dehydration. Additionally, it should be temporarily discontinued before and after tests using iodinated contrast media. It is safest for pregnant women or those who are breastfeeding not to use this medication. This medication can cause lactic acidosis, which is rare but very serious, so if symptoms such as muscle pain, difficulty breathing, or weakness occur, visit the hospital immediately. While taking this medication, it is important to regularly monitor kidney function and blood tests to detect any abnormalities. This medication can induce hypoglycemia, so caution should be exercised during meals or increased physical activity, and the risk of hypoglycemia may be heightened when taken with other hypoglycemic agents. Alcohol consumption can increase the risk of lactic acidosis, so avoid drinking during treatment with this medication. In cases of surgery or severe illness, this medication should be temporarily discontinued, and resumed once the patient is stabilized. Patients taking this medication should consult a doctor immediately if blisters on the skin or severe joint pain occur. Finally, elderly patients may need dose adjustments and regular monitoring due to the possibility of decreased kidney function.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, rash, Stevens-Johnson syndrome (exfoliative skin disorder), acute pancreatitis (including fatal/non-fatal hemorrhagic or necrotizing pancreatitis), difficulty breathing, acute renal failure (occasionally requiring dialysis), severe and disabling joint pain, blistering pseudoporphyria, thrombocytopenia, lactic acidosis, hepatic abnormalities (elevated liver enzymes and jaundice), acute renal failure, difficulty breathing, unstable angina

Mild side effects

• Diarrhea
• upper respiratory infection
• headache
• nausea
• vomiting
• abdominal pain
• constipation
• nasopharyngitis
• pruritus
• myalgia

This medication should be stored in a tightly sealed container that is air-tight, at a temperature between 1 and 30 degrees Celsius. Proper storage maintains the effectiveness of the medication for a longer period.

Appearance

Pink oval film-coated tablets

Package unit

30 tablets/box [10 tablets/PTP x 3]