K-Cab Oral Disintegrating Tablet 50 mg (Tegoprazan)

Adult dose

Administer as follows to adults. Treatment of erosive gastroesophageal reflux disease: Administer 50 mg orally once daily for 4 weeks. For patients whose esophagitis has not healed or whose symptoms persist, administer for an additional 4 weeks. Treatment of non-erosive gastroesophageal reflux disease: Administer 50 mg orally once daily for 4 weeks. Treatment of gastric ulcers: Administer 50 mg orally once daily for 8 weeks. Antibiotic combination therapy for Helicobacter pylori eradication in patients with peptic ulcers and/or chronic atrophic gastritis: Patients with Helicobacter pylori infection should receive eradication therapy. Administer this medicine 50 mg, amoxicillin 1 g, and clarithromycin 500 mg orally twice daily for 7 days. Maintenance therapy after treatment of erosive gastroesophageal reflux disease <limited to 25mg>: Administer 25 mg orally once daily. This medicine may be administered with or without food. Patients with hepatic impairment: No dose adjustment is necessary in patients with mild hepatic impairment according to the Child-Pugh classification. This medicine is an orally disintegrating tablet. Place it on the tongue and allow it to dissolve in saliva, or take it with water. If oral administration of this medicine is difficult, place it in a syringe with approximately 10 mL of water, gently shake to disperse, and administer immediately into the stomach through a nasogastric tube. To ensure no residue remains, add an additional 20 mL of water to the syringe and repeat administration through the nasogastric tube.

This drug should not be used in certain patients. Patients with allergies to this drug or its components or who have experienced hypersensitivity reactions should not take it. Furthermore, patients taking certain antiviral agents (atazanavir, nelfinavir, rilpivirine) should avoid using this medication together, as it may reduce its effectiveness. Women who are pregnant or breastfeeding should also avoid taking this drug. Patients with severe liver disease should use this drug cautiously, and safety has not been fully established for patients with impaired kidney function. Older adults should be cautious since liver and kidney functions can decline. Various side effects may occur during treatment with this drug. Common side effects include nausea, diarrhea, and dyspepsia, with reports of neurological symptoms such as headaches and dizziness. Rarely, symptoms such as skin rash, muscle pain, fatigue, and cough may appear. As this drug suppresses gastric acid secretion, it can lead to vitamin B12 deficiency with prolonged use. Additionally, the reduction in gastric acid may slightly increase the risk of bacterial infections in the stomach; therefore, if diarrhea persists, consult a doctor. With long-term administration, there may be an increased risk of gastric polyps or fractures related to osteoporosis, so regular check-ups are recommended if necessary. Particularly, when taken for more than 3 months, monitoring of serum magnesium levels is necessary as lower levels may occur. This drug can interact with other medications, so if you are taking certain antiviral agents, antifungals, iron supplements, etc., it is essential to inform healthcare professionals. Pregnant or breastfeeding women should avoid taking this medication, and safety in children and adolescents has not been sufficiently established. While no severe side effect cases have been reported with overdose, if suspected, seek medical attention immediately for appropriate treatment. This drug should be kept out of reach of children, and transferring it to another container can compromise its quality.

• Nausea
• diarrhea
• indigestion
• nasopharyngitis
• viral upper respiratory infection
• chest discomfort
• epigastric pain
• abdominal discomfort
• constipation
• abdominal pain

This drug should be stored in a tightly closed container to prevent exposure to air or moisture, preferably at room temperature between 1 degree and 30 degrees Celsius. This will help maintain the drug's effectiveness for a long time.

Appearance

White, round, convex oral disintegrating tablet

Package unit

Bottle - 30 tablets/bottle, PTP - 28 tablets/box [7 tablets/PTPX4]