Sitagliptin Metformin Tablets 50/1000 mg

Adult dose

This medication is typically taken twice daily with food, and the dosage is gradually increased to reduce gastrointestinal side effects caused by metformin. 1. Patients not currently treated with metformin: The initial dose is 50/500 mg taken twice daily, one tablet at a time, which can be increased to 50/1000 mg taken twice daily, one tablet at a time. 2. Patients currently on metformin therapy: Sitagliptin

This medication contains both sitagliptin and metformin and is used to help control blood glucose in patients with type 2 diabetes. While taking this medication, there may be a risk of severe hypersensitivity reactions, so if any allergic symptoms, skin rashes, or breathing difficulties occur, you should immediately stop taking it and seek medical attention. Acute pancreatitis may occur, so you should inform your doctor if you experience symptoms such as abdominal pain, vomiting, or loss of appetite. Patients with severe renal impairment or acute heart failure, acute myocardial infarction, or severe infection should not take this medication, and it may need to be temporarily discontinued before and after surgery. Women who are pregnant or may become pregnant, and breastfeeding women should avoid taking this medication for safety. This medication may cause hypoglycemia; therefore, it is important to have regular meals and be cautious during intense exercise. When used in combination with other hypoglycemic agents, the risk of hypoglycemia may increase, so dosage adjustments according to a doctor's instructions are necessary. Alcohol consumption may increase the risk of lactic acidosis; therefore, alcohol should be avoided while taking this medication. Regular renal function tests are needed as there may be a decrease in renal function, and blood tests are recommended as vitamin B12 deficiency may occur. Additionally, if any unusual symptoms such as blistering of the skin or severe joint pain occur while on medication, you should consult a doctor immediately. There may be drug interactions; therefore, if you are taking other medications, you must inform your doctor or pharmacist, and you should notify medical personnel immediately if any unusual symptoms develop during medication.

Serious side effects

• Urticaria
• angioedema
• anaphylaxis
• Stevens-Johnson syndrome
• exfoliative skin disease
• acute pancreatitis
• lactic acidosis
• acute renal failure
• shortness of breath
• unstable angina

Mild side effects

• Diarrhea
• upper respiratory infection
• headache
• nausea
• vomiting
• abdominal pain
• nasopharyngitis
• constipation
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container that is not exposed to air, at a temperature between 1 and 30 degrees Celsius. Storing it this way maintains the medication's effectiveness and prevents deterioration.

Appearance

Pink oval film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)]