Sinuvim Tablet 50/500 mg (Sitagliptin, Metformin)

Adult dose

This medication is generally taken twice daily with food, and the dosage should be gradually increased to reduce gastrointestinal adverse reactions caused by metformin. 1. Patients currently not receiving metformin: - Initial dose is 50/500 mg of this medication, taken 1 tablet twice daily. - For dose escalation, use 50/1000 mg of this medication, 1 tablet twice daily. 2. Patients receiving metformin treatment:

This medication contains sitagliptin and metformin, and is used for the treatment of diabetes. First, allergic reactions may occur when taking this medication, so if skin rashes, itching, or breathing difficulties arise, you should immediately discontinue use and consult a doctor. Additionally, acute pancreatitis may cause inflammation of the pancreas, so if you experience abdominal pain, vomiting, or severe abdominal discomfort after starting the medication, you should visit a hospital immediately. The metformin component can rarely cause a serious metabolic disorder called lactic acidosis, so if you experience symptoms such as difficulty breathing, muscle pain, weakness, or abdominal pain, you should immediately stop taking the medication and consult a healthcare professional. This medication should not be administered to patients with impaired kidney function, severe liver disease, acute heart failure, dehydration, severe infections, pregnant women, or nursing mothers, and you must inform healthcare professionals if you have any of these conditions. Regular kidney function tests should be performed while using this medication, and it should be discontinued if kidney function worsens. Additionally, this medication can cause hypoglycemia, so caution is advised during irregular meals or intense exercise, and the risk of hypoglycemia may increase when used in combination with other blood sugar-lowering agents, so careful monitoring of blood sugar levels is essential. It is advisable to avoid alcohol intake while using this medication, and it is recommended to temporarily discontinue use during surgeries or radiological examinations. Rarely, severe joint pain or skin blistering conditions may occur, so if any of these symptoms appear, you should notify your doctor immediately. While taking this medication, it is important to have regular blood tests and kidney function checks, and to consult healthcare professionals if there are any abnormal symptoms.

Serious side effects

• Hives
• anaphylaxis
• angioedema
• exfoliative skin disease
• Stevens-Johnson syndrome
• acute pancreatitis
• acute renal failure
• difficulty breathing
• unstable angina
• severe joint pain with disability

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory infection
• nasopharyngitis
• headache
• hypoglycemia
• constipation
• weakness

This medication should be stored in a sealed container to prevent exposure to air and moisture, preferably at room temperature between 1 to 30 degrees Celsius. This will help maintain the medication's efficacy and prevent deterioration.

Appearance

Bright pink oval film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)]