PosiCombi Tablet 10/100 Milligrams

Adult dosage

This medication can be administered as 1 tablet once daily without regard to meals for patients taking sitagliptin 100 mg and dapagliflozin 10 mg. The tablet should be swallowed whole.

This medication contains two components that help in blood sugar control and is used for the treatment of diabetes. While taking this medication, allergic reactions may occur, so if symptoms such as rash, itching, or difficulty breathing arise, stop taking it immediately and consult a doctor. There is a risk of developing a serious inflammation of the pancreas called pancreatitis, so if symptoms such as abdominal pain, nausea, or vomiting arise, inform a healthcare provider immediately. This medication is not recommended for patients with certain genetic disorders, type 1 diabetes, diabetic ketoacidosis, or patients undergoing dialysis. Patients with reduced kidney function or the elderly require dosage adjustments and periodic kidney function tests, and should be cautious of the risk of fluid depletion and hypotension. During treatment, the risk of genital and urinary infections may increase, so appropriate treatment should be sought for any infection symptoms. Hypoglycemic symptoms may occur, so blood sugar levels should be monitored carefully, especially when taken with other hypoglycemic agents such as insulin or sulfonylureas. It is advised that pregnant or breastfeeding women do not use this medication, and it should be discontinued immediately if pregnancy is confirmed. The elderly are at higher risk of decreased kidney function, so regular kidney function tests are necessary, and dosage adjustments should be made with caution. In case of overdose, there is no specific antidote, so treatment should be symptomatic and in accordance with healthcare provider instructions. There is generally no significant effect of this medication when taken alone on driving or operating machinery, but caution is necessary due to the risk of hypoglycemia when used with other hypoglycemic agents. The safety and efficacy of this medication have not been established in children, so it is not recommended for individuals under 18 years of age. Store the medication in its original container and keep it out of reach of children.

Serious side effects

• Hives
• severe swelling (edema)
• chest tightness
• difficulty breathing
• cold sweat
• pallor
• anaphylaxis
• angioedema
• Stevens-Johnson syndrome
• exfoliative dermatitis

Mild side effects

Hypoglycemia, dizziness, constipation, dry mouth, back pain, polyuria, nocturia, vulvar itching, genital itching, increased hematocrit, decreased renal creatinine clearance at the beginning of treatment, dyslipidemia, elevated serum creatinine, elevated blood urea, weight loss, upper respiratory infection, nasopharyngitis, headache, diarrhea, nausea, abdominal pain, vomiting, dyspepsia, vertigo, palpitations, insomnia, tinnitus, menstrual irregularities, vaginal discharge, itching

This medication should be stored in a tightly closed container to protect it from air and moisture, and it is best stored at room temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain its effectiveness.

Appearance

Yellow, rectangular film-coated tablets

Package unit

28 tablets/box [(7 tablets/PTP x 4)], 30 tablets/box [(10 tablets/PTP x 3)]