Dapagliflozin and Sitagliptin Tablets 10/100 mg

Adult dosage

This medication can be administered to patients receiving sitagliptin 100 mg and dapagliflozin 10 mg once daily, independent of meals, with one tablet taken at a time. The tablet should be swallowed whole.

This medication may cause allergic reactions; therefore, if symptoms such as skin rashes or difficulty breathing occur after administration, stop taking the medication immediately and consult a doctor. This medication carries a risk of severe pancreatitis, so if symptoms of abdominal pain, nausea, or vomiting appear during treatment, seek medical attention immediately. This medication should not be used in patients with allergies to certain components, type 1 diabetes patients, those with lactose intolerance, and patients undergoing dialysis. Patients with reduced fluid volume or impaired renal function should consult a physician before taking this medication, and should periodically check for symptoms of hypotension or changes in renal function during treatment. This medication may increase the risk of genital and urinary tract infections; therefore, if symptoms of infection occur, immediate treatment should be sought, and patients with a history of infections should use caution. Hypoglycemic symptoms may occur while taking this medication, especially when used in combination with insulin or sulfonylurea, so blood sugar levels should be checked frequently and symptoms closely monitored. Women who are pregnant or planning to become pregnant should avoid using this medication, and nursing women should also refrain from taking it. Elderly patients may experience decreased renal function, so regular renal function testing is recommended before and during treatment with this medication. There is no specific antidote for overdose of this medication; thus, appropriate treatment should be provided according to symptoms, following a doctor's instructions. Precautions should be taken when driving or operating machinery due to the risk of hypoglycemia, especially when combined with other hypoglycemic agents.

Serious side effects

Urticaria, severe swelling (edema), anaphylaxis, angioedema, severe skin reactions, Stevens-Johnson syndrome, acute pancreatitis, fatal/non-fatal hemorrhagic or necrotizing pancreatitis, acute renal failure, worsening renal function, urospesis, pyelonephritis, severe edema, hypertension, headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, shortness of breath or difficulty breathing, asthmatic episodes, cough with fever

Mild side effects

• Hypoglycemia
• dry mouth
• constipation
• dizziness
• back pain
• polyuria
• nocturia
• itching in the external genitalia
• itching in the genital area
• increased hematocrit

This medication can be sensitive to air or humidity, so it should be stored in a tightly sealed container. It is best to keep it at room temperature between 1°C and 30°C. This helps maintain the effectiveness of the medication for a longer period.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/box - 30 tablets/box[(10 tablets/PTP x 3)], 28 tablets/box - 28 tablets/box[(7 tablets/PTP x 4)]