Litesitamet Tablet 50/1000 mg

Adult dose

This medication is typically taken twice daily with food, and the dosage is gradually increased to reduce gastrointestinal side effects caused by metformin. The initial dose is determined based on the patient's current treatment regimen. 1. For patients not treated with metformin: The initial dose is 50/500 mg of this medication taken twice daily, increasing to 50/1000 mg, one tablet each time.

This medication contains sitagliptin and metformin, which require caution during use. First, this medication may cause allergic reactions, so if symptoms like hives, rash, or difficulty breathing occur, discontinue use immediately and consult a physician. There is a risk of acute pancreatitis, which is inflammation of the pancreas, so be vigilant for symptoms like abdominal pain, nausea, and vomiting, and stop taking the medication right away if suspected. Moreover, this medication should not be administered to patients with severe renal impairment, acute heart failure, or myocardial infarction, and it should be temporarily stopped before and after surgeries or examinations using radioactive iodine contrast agents. It is advisable not to use it in pregnant or breastfeeding women or in children and adolescents under 18 years of age, as safety has not been established. Regular monitoring of renal function is necessary while on this medication, especially for the elderly or patients with weakened kidney function. Additionally, this medication may cause hypoglycemia, so blood sugar levels should be carefully monitored in cases of irregular meal patterns, vigorous exercise, or when taken with other blood sugar-lowering agents. Alcohol consumption may increase the risk of lactic acidosis, so excessive drinking should be avoided, and symptoms like malaise, muscle pain, respiratory distress, and abdominal pain should be reported to medical personnel immediately. During the course of this medication, rare side effects like severe joint pain or bullous pemphigoid may occur; if these symptoms occur, inform a doctor immediately. Finally, this medication may interact with various drugs, so if other medications are being taken, it is essential to consult with a physician or pharmacist, particularly when using drugs that might affect kidney function.

Serious side effects

• Hives, severe swelling (angioedema), anaphylaxis, rash, skin vasculitis, exfoliative skin conditions like Stevens-Johnson syndrome, severe allergic reactions
• Acute pancreatitis (including fatal or non-fatal hemorrhagic or necrotizing)
• Acute kidney failure, acute deterioration in kidney function
• Respiratory distress
• Liver dysfunction (including elevated liver enzymes, jaundice)
• Acute and unstable heart failure
• Severe lactic acidosis
• Severe hypoglycemia (accompanied by altered consciousness or seizures)
• High

Mild side effects

• Diarrhea
• upper respiratory tract infections
• headache
• nausea
• vomiting
• abdominal pain
• nasopharyngitis
• constipation
• muscle pain
• limb pain

This medication should be kept in a tightly closed container to prevent air or moisture from entering, and it is best stored at a temperature between 1°C and 30°C at room temperature. By doing so, the effectiveness of the medication can be maintained, and degradation can be prevented.

Appearance

Brown oval film-coated tablet engraved with 751 on one side

Package unit

30 tablets/box [(10 tablets/PTP x 3)]