Rabeanu Tablet 20/500 mg

Adult dose

Gastric ulcer, duodenal ulcer: Administer 10/500 mg orally once daily to adults. Depending on symptoms, 20/500 mg may be administered once daily. Treatment duration is typically up to 8 weeks for gastric ulcers and 6 weeks for duodenal ulcers. Erosive or ulcerative gastroesophageal reflux disease: Administer either 10/500 mg or 20/500 mg once daily for 4 to 8 weeks. If not treated, an additional 8-week course of 10/500 mg may be administered.

Child dose

Safety in pediatric patients has not been established.

This medication should not be administered to certain patients. Patients who are allergic to this drug or any of its components or have had hypersensitivity reactions should not use it. Additionally, it should not be given to patients taking atazanavir or rilpivirine, and to women who are pregnant or breastfeeding. Patients with liver dysfunction, impaired kidney function, the elderly, and those with poor heart or lung function should use this drug cautiously. Particular care is required for those with electrolyte imbalances or who need to limit sodium intake. During the course of treatment, allergic reactions such as skin rash, hives, or itching may occur, so if symptoms arise, discontinue use immediately. Regular blood tests are recommended as changes in red or white blood cell counts or increased liver function tests may occur. Various side effects such as cardiac-related abnormal symptoms, gastrointestinal symptoms, headaches, dizziness, shortness of breath, muscle pain, and joint pain may arise, so it is essential to consult with healthcare professionals if any abnormal symptoms occur. This medication suppresses gastric acid secretion, which may increase the risk of osteoporosis-related fractures with long-term use. Additionally, hypomagnesemia can occur due to lowered magnesium levels, so regular monitoring of serum magnesium concentrations is needed when taking this for an extended period or in conjunction with specific medications. With a decrease in gastric acid, the risk of gastrointestinal bacterial infections may slightly increase, and if diarrhea symptoms persist, Clostridium difficile infection should be suspected. This medication does not significantly affect driving or machine operation, but caution is needed due to possible drowsiness. There may be interactions when this drug is combined with other medications, so it is crucial to inform the medical staff about any other medicines being taken, particularly with warfarin, methotrexate, atazanavir, or rilpivirine, which should be used cautiously or not at all. It should not be used in pregnant or breastfeeding women, and caution is required for the elderly due to the higher incidence of side effects from liver function deterioration. These tablets should be swallowed whole without chewing or crushing and must be kept out of reach of children. With long-term use, there may be the potential for symptoms of malignant tumors to be masked or diagnoses to be delayed, so consult healthcare professionals for any abnormal symptoms. Additionally, the risk of gastric polyps may increase with prolonged use; therefore, it is advised to maintain the treatment duration and dosage at minimal levels. No specific antidote exists for overdose, but appropriate treatment should be administered based on symptoms, and regular blood and liver function tests are advisable.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in the mucous membranes of the mouth/eyes, severe skin reactions, asthma attacks, respiratory abnormalities with cough + fever, jaundice (yellowing of skin or eyes), profound lethargy, liver abnormalities (jaundice), sudden and very severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, severe

Mild side effects

• Rash
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia
• petechiae

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. The storage temperature should be kept between 1 to 30 degrees Celsius at room temperature, and it is advisable to avoid places that are too hot or too cold.

Appearance

Brownish-yellow oval film-coated tablet

Package unit

28 tablets/bottle