Posita Tablet 10/100 mg

Adult dosage

This medication can be administered at a dose of 1 tablet once daily to patients receiving Sitagliptin 100 mg and Dapagliflozin 10 mg, irrespective of meals. The tablet should be swallowed whole.

This medication contains Sitagliptin and Dapagliflozin, which are used for diabetes treatment. Sitagliptin may rarely cause severe allergic reactions; therefore, if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur within 3 months of administration, it should be discontinued immediately and the physician consulted. Additionally, acute pancreatitis may occur, so symptoms such as abdominal pain, nausea, or vomiting should be reported to a physician immediately. This medication is not to be used in patients with type 1 diabetes or diabetic ketoacidosis, nor in patients with lactose intolerance or certain genetic metabolic disorders, or those undergoing dialysis. Dapagliflozin can cause blood pressure reduction or kidney damage in patients with reduced fluid volume or renal impairment, so fluid status and kidney function should be regularly monitored before and during administration. Furthermore, Dapagliflozin may increase the risk of genital and urinary infections, so if related symptoms occur, prompt treatment should be sought. There is a risk of hypoglycemia; therefore, when used in combination with insulin or sulfonylureas, symptoms of hypoglycemia should be monitored closely, and dosage adjustments may be needed. Women who are pregnant or nursing are advised to avoid using this medication, especially during breastfeeding, as it may be transmitted through breast milk and affect the baby. Elderly patients may have a higher likelihood of renal function decline, so dosage adjustments and kidney function tests are necessary. In case of overdose, immediate medical attention should be sought for appropriate treatment; some components may be removed by dialysis, but symptomatic treatment is generally required. While taking this medication, caution is advised when driving or operating machinery due to the risk of hypoglycemic symptoms. Finally, this medication has not established safety and efficacy in children, so it should not be administered to those under 18 years of age. Always take this medication according to the physician's instructions and consult a physician or pharmacist immediately if any unusual symptoms occur.

Serious side effects

Urticaria, severe swelling (edema), anaphylaxis, angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in the oral/ocular mucosa, severe skin adverse reactions, asthma attack, cough with accompanied fever indicating respiratory abnormalities, yellowing of the skin or eyes (jaundice), profound lethargy, liver abnormalities, sudden and severe headache, thunderclap headache, seizures, loss of consciousness

Mild side effects

Hypoglycemia, dizziness, constipation, dry mouth, lower back pain, polyuria, nocturia, itching of the vulva, itching of the genitals, increased hematocrit, reduced plasma creatinine clearance at the beginning of treatment, dyslipidemia, increased serum creatinine, increased blood urea, weight loss, nausea, diarrhea, dyspepsia, malaise, vomiting, cough, palpitations, anxiety disorders, enuresis, insomnia, tinnitus, oral headache, orthostatic hypotension, headache, rhinitis,

This medication should be stored in a sealed container to protect it from air and moisture, and it is recommended to keep it at room temperature between 1 degree and 30 degrees Celsius. This storage helps maintain the effectiveness of the medication and ensures safe usage.

Appearance

Yellow oblong film-coated tablet

Package unit

28 tablets/box - 28 tablets/box [(7 tablets/PTP x 4)], 30 tablets/box - 30 tablets/box [(10 tablets/PTP x 3)]