Medication info
Cantabel A Tablet 8/5/20 mg

Cantabel A Tablet 8/5/20 mg

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›8mg / 1 tabletAmlodipine Besylate›6.94mg / 1 tabletAtorvastatin Calcium›21.7mg / 1 tablet
Manufacturer / importer
(주)종근당
Appearance
Bright yellow, oval film-coated tablet
Packaging
30 tablets/PTP
Approval status
Active

MFDS item code 202200402 · Approved 2022.01.24 · Insurance code 643308920

Summary

Main use
Reduction of hypertension and cardiovascular disease risk, improvement of dyslipidemia
Who takes it
Adults
Adult dose
This medication is taken once daily, 1 tablet with or without food. It is recommended to take it at the same time each day (e.g., in the morning). Dosage should be individualized for each patient based on the efficacy and tolerability of Candesartan Cilexetil/Amlodipine combination and Atorvastatin. Candesartan Cilexetil/Amlodipine Combination - 8/5 mg: Administer 8 mg of Candesartan Cilexetil or 5 mg of Amlodipine for patients not properly controlling blood pressure.

Ingredients

Manufacturer
(주)종근당

Efficacy & effects

Reduction of hypertension and cardiovascular disease risk, improvement of dyslipidemia

  • Essential hypertension
  • primary hypercholesterolemia
  • mixed dyslipidemia
  • primary dysbeta-lipoproteinemia
  • elevated serum triglycerides
  • homozygous familial hypercholesterolemia
View approved original text

This medication is used for adults with essential hypertension who cannot control blood pressure solely with Candesartan Cilexetil and Amlodipine combination. Additionally, the Atorvastatin component reduces the risk of myocardial infarction, stroke, and vascular surgery in adults with coronary heart disease and those with type 2 diabetes, protecting cardiovascular health. Moreover, it helps improve dyslipidemia in patients with hyperlipidemia by lowering LDL cholesterol and total cholesterol levels and increasing HDL cholesterol levels. This combination is effectively used for the prevention and treatment of cardiovascular diseases by managing blood pressure and lipids simultaneously.

How to take

Adult dose

This medication is taken once daily, 1 tablet with or without food. It is recommended to take it at the same time each day (e.g., in the morning). Dosage should be individualized for each patient based on the efficacy and tolerability of Candesartan Cilexetil/Amlodipine combination and Atorvastatin. Candesartan Cilexetil/Amlodipine Combination - 8/5 mg: Administer 8 mg of Candesartan Cilexetil or 5 mg of Amlodipine for patients not properly controlling blood pressure.

Precautions

This medication can cause serious harm to the fetus and newborn if taken during pregnancy; therefore, it should be discontinued immediately upon confirmation of pregnancy. If muscle problems occur or muscle enzyme levels significantly increase, this medication should be stopped. Patients at higher risk of myopathy, such as those with infections, hypotension, surgeries, trauma, etc., need to exercise caution. Patients with allergies to any components of this drug, women who are pregnant or breastfeeding, or those with severe liver disease or certain renal impairments should not take this medication. Seniors, patients with hyperkalemia, patients with impaired liver function, those with hypotension, heart valve disease, and patients with diminished kidney function should take this medication with greater care, requiring regular blood pressure and kidney function checks. This medication lowers blood pressure, so it should be avoided in patients with hypotension or shock symptoms; if blood pressure becomes too low, appropriate measures should be taken under medical advice. During treatment, side effects such as muscle pain, muscle weakness, dizziness, headache, edema, dyspepsia, and liver function abnormalities may occur; consult a doctor if these symptoms persist or worsen. Additionally, some components of this medication can affect the liver or muscles, so regular liver function and muscle enzyme tests should be performed, and if abnormal symptoms appear, discontinuation is advised. This medication can interact with other drugs, so it is crucial to inform a doctor or pharmacist of any current medications taken, especially when used with antihypertensives, lipid-lowering agents, antibiotics, antifungals, or immunosuppressants. Grapefruit juice may increase the concentration of this medication in the blood, so it is advisable to avoid consuming grapefruit juice. Caution is advised when driving or operating machinery as dizziness or drowsiness may occur. Regular check-ups and adherence to medical advice during usage are important, and any abnormal symptoms should be promptly reported.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, cough with fever indicating respiratory issues, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urination problems

Mild side effects

  • Dizziness
  • headache
  • syncope
  • chest pain
  • edema
  • palpitations
  • urinary tract infection
  • gastrointestinal pain
  • increased blood pressure
  • gastrointestinal pain
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  • orthostatic hypotension
  • flushing
  • fatigue
  • palpitations
  • drowsiness
  • nausea
  • weakness
  • lethargy
  • weight gain/loss
  • tension
  • sensory loss/paresthesia
  • taste disturbance
  • dry mouth
  • dyspepsia
  • hair loss
  • sweating
  • purpura
  • skin discoloration
  • angioedema
  • increased urinary frequency
  • urinary disorders
  • nocturia
  • hepatitis
  • blurred vision
  • tinnitus

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent air or moisture exposure, at room temperature between 1 and 30 degrees Celsius, to maintain its effectiveness and safety.

Appearance and packaging

Appearance

Bright yellow, oval film-coated tablet

Package unit

30 tablets/PTP

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.