Billguard 50 mg (Vildagliptin)

Adult dose

This drug is administered as 50 mg once daily in the morning or as 100 mg divided into 50 mg doses twice daily in the morning and evening. When used in combination with metformin or thiazolidinediones, the dosage is 100 mg per day, taken as 50 mg doses twice daily in the morning and evening. When combined with sulfonylureas, the recommended dose is 50 mg once daily in the morning. When combined with both sulfonylureas and metformin, a dosage of 100 mg once daily has not been more effective than 50 mg once daily in this patient group. When sufficient blood sugar control cannot be achieved with combination therapy of sulfonylureas and metformin, the recommended dosage is 100 mg per day, taken as 50 mg doses twice daily in the morning and evening. When sufficient blood sugar control cannot be achieved with insulin (either alone or in combination with metformin), the recommended dosage is 100 mg per day, taken as 50 mg doses twice daily in the morning and evening. This drug can be taken regardless of meals, and dosages exceeding 100 mg per day are not recommended. When taken with sulfonylureas, a reduction in the sulfonylurea dosage may be necessary to reduce the risk of hypoglycemia. If a dose is missed, take it as soon as remembered and return to the regular schedule for the next dose. If it is close to the next dosing time, do not take the missed dose. Do not double up to make up for missed medication.

This drug should not be used in patients who are allergic to the active substance or other ingredients. It should also not be administered to patients with type 1 diabetes or diabetic ketoacidosis. Because this drug contains lactose, it should not be used in patients with lactose intolerance or genetic lactose-related issues. While using this drug, there may rarely be abnormal liver function, so regular liver function tests should be performed before and during administration. If liver function levels persist at three times the normal upper limit or symptoms such as jaundice appear, the use of this drug should be stopped. In some heart failure patients, the use of this drug is not recommended, so consult a physician if there is a history of heart disease. Skin lesions such as blisters or ulcers may appear, so the condition of the skin should be carefully monitored. There is a risk of acute pancreatitis, so if symptoms such as abdominal pain or vomiting occur, immediate medical attention should be sought. When used with medications that can cause hypoglycemia, such as sulfonylureas, caution for hypoglycemic symptoms should be exercised, and dosage adjustments may be necessary. If symptoms such as dizziness occur, it is advisable to avoid driving or operating machinery. It is not safe for pregnant or breastfeeding women to use this drug. There is no need for special dosage adjustments in the elderly; however, safety and efficacy have not been established in children and adolescents, so it is not recommended. In cases of overdose, supportive measures are necessary, and this drug is not removed by dialysis, so caution is advised. Keep out of reach of children and be careful not to transfer it to another container.

Serious side effects

Hives, angioedema, blistering and exfoliative skin lesions (including bullous pemphigoid), hepatitis, jaundice, acute pancreatitis, heart failure, peripheral edema, severe allergic reactions, shortness of breath, acute myocardial infarction, acute cholecystitis, pulmonary edema, chest discomfort, dizziness, renal impairment, lip blisters

Mild side effects

• Headache
• dizziness
• tremor
• nausea
• fatigue
• constipation
• asthenia
• weight gain
• gastroesophageal reflux
• diarrhea

This drug is sensitive to air and moisture, so keep the bottle tightly closed and sealed. It is also recommended to store in a cool place below 30 degrees Celsius.

Appearance

White to light yellow circular tablet

Package unit

30 tablets/box [10 tablets/PTP X 3]