Sitaro M Tablets 50/850 mg (Sitagliptin Hydrochloride Monohydrate, Metformin Hydrochloride Colloidal Silicon Dioxide)

Adult dose

This medication is generally taken twice daily with meals, and to reduce gastrointestinal side effects caused by metformin, the dosage is gradually increased. 1. Patients currently not receiving treatment with metformin: The initial dosage is 50/500 mg of this medication to be taken twice a day, 1 tablet at a time, which may be increased to 50/1000 mg taken twice a day, 1 tablet at a time. 2. Patients treated with metformin:

This medication may cause allergic reactions; therefore, if symptoms such as skin rash, hives, or difficulty breathing appear, you must immediately discontinue use and consult a physician. Additionally, there are rare reports of severe side effects such as pancreatitis, which is inflammation of the pancreas; if abdominal pain or vomiting occurs while taking this medicine, notify healthcare providers immediately. This medication should not be taken by patients with impaired kidney function or severe infections, heart failure, acute myocardial infarction, etc., and kidney function should be checked regularly. When undergoing imaging tests using radiographic contrast agents, this medication should be temporarily discontinued before and after the test, and it should be resumed only after confirming that kidney function is normal. Pregnant women or those who may become pregnant, as well as nursing mothers, should not take this medication for safety. While on this medication, it is necessary to be cautious as irregular eating, excessive exercise, and concomitant use of other blood sugar-lowering agents may lead to hypoglycemia. Due to the metformin component, rare but serious metabolic abnormalities such as lactic acidosis may occur, so if symptoms like fatigue, muscle pain, difficulty breathing, or abdominal pain occur, notify healthcare providers immediately. Alcohol consumption may increase the risk of side effects from this medication, so it is advisable to avoid drinking while on it. If surgery is to be performed, this medication should be stopped 48 hours before surgery, and it can be resumed only after confirming the patient's condition is stable and kidney function is normal post-surgery. This medication may cause side effects such as gastrointestinal disturbances, headaches, and upper respiratory infections, and hypoglycemic symptoms may also occur; therefore, it is essential to consult a healthcare provider immediately if symptoms occur. Regular blood tests and kidney function tests are required, and especially in the elderly, careful monitoring is vital due to the higher risk of side effects related to decreased kidney function. In case of overdose of this medication, one must immediately visit a hospital for appropriate treatment, and some components may be removed through dialysis. If severe joint pain or blistering skin symptoms appear during treatment, you must immediately discontinue the medication and consult a specialist.

Serious side effects

• Urticaria
• angioedema
• anaphylaxis
• Stevens-Johnson syndrome
• exfoliative skin disease
• acute pancreatitis
• acute renal failure
• severe hypersensitivity reactions
• difficulty breathing
• acute renal failure

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory infection
• nasopharyngitis
• headache
• myalgia
• limb pain
• back pain

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture and should be kept at room temperature between 1 and 30 degrees Celsius for safety. Storing this way can help maintain the efficacy of the medication for a longer period.

Appearance

Pink oval film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)]