Dovem 250 mg (Dovesil Calcium Hydrate)

Adult dose

Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular damage and retinopathy: 500~1000mg daily 2. Venous disease: Administer 750mg daily for 1~3 weeks, followed by 500mg daily. Administer after meals with plenty of fluids. The dose may be adjusted as appropriate according to age and symptoms.

This medication should not be used by individuals allergic to this medication or any of its ingredients. This medication contains lactose, so individuals with genetic disorders that inhibit lactose breakdown should not take it. Patients with poor kidney function should use this medication with caution. Since this medication is excreted through the kidneys, the dosage may need to be reduced in cases of severe renal impairment. Patients with impaired liver function should also exercise caution while using this medication, and if liver enzyme levels increase, treatment should be re-evaluated. This medication contains sodium bisulfite, which can cause severe allergic reactions in individuals allergic to sulfites or asthmatics, so caution is necessary. Common side effects while taking this medication may include headache, abdominal pain, nausea, diarrhea, vomiting, joint pain, muscle pain, fever, chills, lethargy, and fatigue. Elevated alanine aminotransferase may also occur. Rarely, blood abnormalities may occur, leading to increased susceptibility to infections. If symptoms of infection, such as high fever or sore throat, emerge, immediate consultation with a physician is advised. In the event of a severe allergic reaction, discontinue use immediately and seek medical assistance. The effects of this medication on driving or operating machinery are not clearly defined, so caution is advised. It is best to avoid this medication during pregnancy, and during breastfeeding, either avoid taking it or discontinue breastfeeding. Safety and efficacy in children have not been established, so it is recommended not to use it in this population. Generally, individuals aged 65 and older can use this medication without special precautions. This medication may affect the results of certain blood tests, so it is important to inform healthcare providers about its use prior to testing.

• Agranulocytosis
• neutropenia
• leukopenia
• skin rash
• allergic dermatitis
• pruritus
• urticaria
• facial edema
• anaphylactic reaction
• headache

This medication is sensitive to air and humidity, so it must be stored in a tightly sealed container. It is important to maintain storage temperatures between 1 to 30 degrees Celsius at room temperature. Proper storage will help preserve the effectiveness of the medication for an extended period.

Appearance

White oval tablet

Package unit

10 tablets/bottle, 30 tablets/bottle, 90 tablets/bottle, 300 tablets/bottle