Sitabaem Tablets 50/1000 mg

Adult dose

The dosage of this medication is determined considering the treatment regimen, efficacy, and tolerability of the patient not exceeding the maximum daily recommended dosage of sitagliptin 100 mg and metformin 2000 mg. Generally, it is taken twice daily with meals, and the dosage is gradually increased to reduce gastrointestinal adverse reactions caused by metformin. 1. For patients not receiving metformin treatment: The initial dose is 1 tablet of 50/500 mg taken twice a day.

This medicine is used for the treatment of diabetes and contains two ingredients: sitagliptin and metformin. Caution is advised for hypersensitivity reactions when taking this medication. Rarely, severe allergic reactions may occur, and if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck appear, discontinue immediately and consult a doctor. Additionally, there is a risk of acute pancreatitis (inflammation of the pancreas), so if symptoms such as abdominal pain, nausea, vomiting, or fever occur, seek medical attention immediately. The metformin component can rarely cause lactic acidosis, a serious metabolic disorder, manifested by symptoms such as muscle pain, difficulty breathing, fatigue, and abdominal pain. Inform healthcare professionals immediately if these symptoms occur. This medication should not be used in patients with severely impaired renal function, acute heart failure, severe infections, or dehydration. Furthermore, it is advisable to temporarily discontinue this medication before and after tests using radiocontrast agents to protect kidney function and to resume only after kidney function returns to normal. It is safest for pregnant or breastfeeding women to avoid taking this medication. During treatment, regular monitoring of kidney function and blood tests should be done, especially for older adults or those with slightly impaired renal function, who should be monitored more often. Due to the risk of hypoglycemia, it is advisable to eat regularly and avoid prolonged fasting or excessive exercise. Hypoglycemia symptoms may occur when taken with other antidiabetic agents or insulin, so blood sugar levels should be monitored closely. The risk of lactic acidosis increases when taken with alcohol, so alcohol consumption should be avoided. It may be necessary to discontinue this medication for a certain period before and after surgery, so consult with healthcare professionals. If severe joint pain or skin blisters appear while taking this medication, inform a doctor immediately and receive treatment. Some patients may experience side effects such as diarrhea, nausea, vomiting, headache, upper respiratory tract infections, rhinitis, constipation, muscle pain, limb pain, back pain, itching, thrombocytopenia, peripheral edema, hypoglycemia, decreased appetite, pruritus, dizziness, and weight loss, and if symptoms are severe, consult with healthcare professionals. In case of overdose, seek emergency treatment immediately; if necessary, drug removal may be performed via dialysis. Finally, during the use of this medication, regular blood sugar testing and health condition monitoring should be carried out to ensure safe and effective treatment.

Serious side effects

Urticaria, severe swelling (angioedema), chest tightness, difficulty breathing, anaphylaxis, severe allergic reactions, rash, severe skin adverse reactions, Stevens-Johnson syndrome, severe rash with fever, blisters, skin peeling, pain of mucous membranes in the mouth/eyes, acute pancreatitis, liver abnormalities (jaundice), acute renal failure, severe edema or urinary abnormalities, severe pain in joints with disability, bullous pemphigoid, serious neurological effects

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• headache
• upper respiratory tract infection
• rhinitis
• constipation
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and it should be kept at room temperature between 1 to 30 degrees Celsius. This ensures the medication's efficacy is maintained and prevents deterioration.

Appearance

Pink oval film-coated tablets

Package unit

30 tablets/box [(10 tablets/PTP x 3)]