Sitavem Tablet 50/500 mg

Adult dose

This medication is typically taken twice a day with meals, and to reduce gastrointestinal adverse reactions caused by metformin, the dosage should be increased gradually. 1. For patients not treated with metformin: The initial dose is one tablet of this medication 50/500 mg taken twice a day; if necessary, it can be increased to 50/1000 mg, taken twice a day. 2. For patients receiving treatment with metformin:

This medication contains sitagliptin and metformin as diabetes therapeutics and has several important precautions during use. First, severe allergic reactions may occur during treatment with this medication; therefore, if symptoms such as rash, hives, difficulty breathing, or swelling of the face or neck appear, discontinue the medication immediately and consult a physician. Second, significant side effects such as acute pancreatitis have been reported, so if symptoms such as abdominal pain, vomiting, nausea, or fever occur, inform healthcare personnel immediately and discontinue the medication. Third, the metformin component can cause lactic acidosis, a rare but potentially fatal metabolic disturbance, so if sudden difficulty breathing, muscle pain, fatigue, or abdominal pain occurs, seek medical attention immediately. Fourth, this medication should not be used in patients with impaired kidney function, severe infections, dehydration, or acute cardiac conditions, and if such conditions occur, discontinue the medication and consult a physician. Fifth, it is safest for women who are pregnant or likely to become pregnant, as well as nursing mothers, to avoid using this medication. Sixth, during the use of this medication, regular kidney function and blood tests should be conducted to monitor health, and vitamin B12 levels should be checked periodically. Seventh, there is a risk of hypoglycemia, so especially when used together with other hypoglycemic agents or insulin, blood sugar levels should be carefully monitored and immediate action should be taken if symptoms arise. Finally, excessive alcohol consumption, intense exercise, and irregular meals should be avoided while taking this medication, and consultation with healthcare personnel is essential regarding the continuation or cessation of medication when undergoing surgery or contrast media tests.

Serious side effects

• Hives
• severe swelling (edema)
• anaphylaxis
• angioedema
• severe allergic reactions
• severe rash accompanied by high fever
• blisters
• skin peeling
• pain in oral/ocular mucosa
• Stevens-Johnson syndrome

Mild side effects

• Diarrhea
• upper respiratory infection
• headache
• nausea
• vomiting
• abdominal pain
• nasopharyngitis
• constipation
• muscle pain
• limb pain

This medication should be kept in a sealed container to protect it from air and moisture, and stored at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication for a long time.

Appearance

Bright pink oval film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)]