Janudam M Tablet 50/1000 mg

Adult dose

This medication is generally taken twice daily with food, and the dosage is gradually increased to reduce gastrointestinal side effects caused by metformin. The initial dosage is determined according to the patient's current treatment regimen. 1. For patients not currently treated with metformin: Take Janudam 50/500 mg twice daily, 1 tablet per dose; the dosage may be increased to 50/1000 mg. 2. For patients currently on metformin:

This medication contains sitagliptin and metformin, diabetes treatment agents; therefore, several precautions must be adhered to while taking it. First, serious allergic reactions may occur during the use of this medication, so if symptoms such as rash, hives, difficulty breathing, or swelling of the face or neck appear, discontinue use immediately and consult a physician. Additionally, there is a risk of developing acute pancreatitis, which causes inflammation of the pancreas, so if experiencing severe abdominal pain, vomiting, or fever, visit a hospital immediately. This medication should not be taken by patients with poor kidney function, acute heart disease, severe infections, or specific diseases; pregnant or breastfeeding women should also avoid it. Regular kidney function tests must be performed during use, and if kidney function rapidly declines, temporarily discontinue use of the medication. Moreover, the metformin component included in this medication can rarely lead to serious metabolic abnormalities known as lactic acidosis, so caution is required in cases of severe dehydration, excessive alcohol consumption, or severe infections. While using this medication, if meal quantities are irregular or physical activity increases suddenly, hypoglycemic symptoms may appear; therefore, blood sugar levels should be checked frequently, and attention should be paid to hypoglycemic symptoms. Furthermore, when used with other hypoglycemic agents or alcohol, the risk of hypoglycemia may increase, so inform healthcare providers about any other medications or alcohol use. Patients scheduled for surgery should stop taking this medication 48 hours prior to surgery and resume only after confirming normal kidney function post-surgery. Finally, gastrointestinal disturbances (diarrhea, nausea, vomiting, etc.), headaches, and upper respiratory tract infections may occur during the use of this medication; consult healthcare providers if symptoms worsen.

Serious side effects

• Hives
• severe swelling (angioedema)
• anaphylaxis
• rash
• skin vasculitis
• Stevens-Johnson syndrome
• acute pancreatitis
• acute renal failure
• difficulty breathing
• unstable angina

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory infection
• nasopharyngitis
• headache
• hypoglycemia
• constipation
• weakness

This medication should be stored in an airtight, sealed container, and it is advisable to keep it at room temperature between 1 and 30 degrees Celsius. This storage method will help maintain the drug's effectiveness and prevent degradation.

Appearance

Pink oval film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)]