Sitamepo Tablet 50/850 mg

Adult dose

This medication is generally taken twice daily with food, with the dosage gradually increased to reduce gastrointestinal adverse reactions caused by metformin. 1. Patients not treated with metformin: The initial dose of this medication 50/500 mg is 1 tablet twice daily, which can be adjusted to 50/1000 mg. 2. Patients currently on metformin treatment: The recommended initial dose is sitagliptin 50 mg

This medication may cause serious allergic reactions at the start of treatment, so if symptoms such as skin rashes or respiratory difficulties occur, use should be discontinued immediately. Moreover, there is a risk of acute pancreatitis, which is inflammation of the pancreas, so it is essential to consult a healthcare professional promptly if symptoms such as abdominal pain or vomiting arise. Patients with impaired kidney function, heart disease, or acute infection should not use this medication, particularly if renal function is below 45 mL/min, it is forbidden to administer. Before and after using iodine contrast agents for tests, this medication should be temporarily discontinued and resumed only after confirming that renal function is normal. Women who are pregnant or breastfeeding should not take this medication, and safety and efficacy in children and adolescents under 18 years of age have not been established. This medication may cause hypoglycemia, so care should be taken with missed meals, irregular eating, or excessive exercise. Patients with impaired liver or kidney function, dehydration or severe infection must take special care as they may experience severe metabolic acidosis known as lactic acidosis. During treatment, it is important to regularly monitor kidney function and blood tests for any abnormalities. Excessive alcohol consumption increases the risk of side effects, so drinking should be avoided while taking this medication. If surgery is planned, use should be discontinued 48 hours prior to the procedure, and resumed only after confirming normal kidney function post-surgery. This medication may increase the risk of hypoglycemia when used with other diabetes medications, so dose adjustments may be needed according to a doctor's instructions. If skin blisters or severe joint pain develop during medication, contact healthcare professionals immediately. In the case of overdose, treatments such as blood dialysis may be necessary, so dosage must be strictly followed. When administering this medication to the elderly, dosage adjustments should be made considering declining kidney function, and regular monitoring is essential.

Serious side effects

• Hives
• severe swelling (angioedema)
• anaphylaxis
• rash
• Stevens-Johnson syndrome
• angioedema
• severe skin reactions
• acute pancreatitis
• acute renal failure
• respiratory difficulties

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory infection
• rhinitis
• headache
• muscle pain
• limb pain
• back pain

This medication should be stored in a tightly sealed container to prevent air or moisture from entering and should be kept at room temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain its effectiveness for a longer period.

Appearance

Pink oval film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)]