Sitamepo Tablets 50/500 mg

Adult dose

This medication is generally taken twice daily with food, and the dosage is gradually increased to reduce gastrointestinal side effects caused by metformin. 1. Patients who are not currently being treated with metformin: - The initial dosage is 1 tablet (50/500 mg) taken twice daily, and it may be increased to 1 tablet (50/1000 mg) taken twice daily. 2. Patients currently receiving metformin: - The recommended initial dosage of this medication for patients unable to achieve adequate blood sugar control with metformin monotherapy is 50 mg of sitagliptin taken twice daily (total daily dosage 100 mg) alongside their existing metformin dosage.

This medication contains sitagliptin and metformin and is used to treat diabetes. First, this medication may cause allergic reactions; if symptoms such as rash, hives, or difficulty breathing occur, you should stop using it immediately and consult a physician. Acute pancreatitis, a serious inflammation of the pancreas, may rarely occur, so if you experience abdominal pain, vomiting, or severe abdominal discomfort, you should inform a healthcare provider immediately. Furthermore, the metformin component may rarely cause a serious metabolic disturbance known as lactic acidosis, so if you experience shortness of breath, severe muscle pain, fatigue, or abdominal pain, you must go to the hospital immediately. This medication should not be administered to patients with severely impaired kidney function, acute heart failure, serious infections, severe liver disease, or to women who are pregnant or breastfeeding. Particularly in cases of compromised kidney function, administration of this medication should be avoided or done with caution, and regular kidney function tests must be performed. Additionally, excessive alcohol consumption should be avoided during treatment; and if surgery is imminent, the medication should be stopped 48 hours prior to the surgery and can be resumed only after confirming normal kidney function post-surgery. This medication poses a risk of hypoglycemia, so regular meals should be maintained, and caution should be exercised during vigorous exercise or if food intake is insufficient. When used in combination with other blood sugar-lowering agents, especially insulin or sulfonylureas, the risk of hypoglycemia increases, so dosages should be adjusted according to a physician's directions. Regular blood sugar, kidney function, and blood tests should be conducted during the use of this medication to monitor for abnormalities, and vitamin B12 levels may decrease, so supplementation may be necessary. Finally, this medication has not established safety and efficacy in children and adolescents; therefore, it should not be used in this demographic. By adhering to these precautions, the benefits of this medication can be enjoyed safely.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, anaphylaxis, severe allergic reactions, severe rash with fever, blistering, skin peeling, pain in mucous membranes of the mouth/eyes, Stevens-Johnson syndrome, respiratory distress, asthma attacks, acute pancreatitis, liver abnormalities (jaundice), sudden and severe headache, seizures, confusion, visual disturbances, paralysis, worsening kidney function, acute kidney failure, lactic acidosis, severe edema

Mild side effects

Diarrhea, nausea, vomiting, abdominal pain, upper respiratory infection, nasopharyngitis, headache, hypoglycemia, constipation, muscle pain, limb pain, back pain, pruritus, thrombocytopenia, decreased appetite, itching, dizziness, arthralgia with severe and disabling symptoms

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. Additionally, avoid storing in extremely hot or cold places; it is recommended to store it at room temperature between 1 degree and 30 degrees Celsius.

Appearance

Light pink oval film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)]