Nexglipin Duo Tablet 50/850 mg

Adult dose

This drug is generally taken twice a day with food, and the dosage is gradually increased to reduce gastrointestinal adverse effects caused by Metformin. 1. Patients not currently being treated with Metformin: Take this drug 50/500 mg 1 tablet twice daily, and may increase to 50/1000 mg 1 tablet twice daily. 2. Patients currently receiving treatment with Metformin

This drug contains Sitagliptin and Metformin and is used for the treatment of type 2 diabetes. When taking this drug, serious allergic reactions may occur, so if symptoms such as skin rash, hives, or difficulty breathing appear, discontinue use immediately and consult a physician. Acute pancreatitis may occur, so inform medical staff immediately if symptoms like abdominal pain, nausea, or vomiting appear. Patients with severe renal impairment or those in acute conditions, dehydration, or severe infection should not take this drug. Additionally, patients with acute cardiovascular issues like acute heart failure, acute myocardial infarction, or sepsis may be at risk if they use this drug. Before and after examinations using iodinated contrast agents, administration of this drug should be temporarily suspended and can only be resumed after kidney function is confirmed to be normal. Pregnant women, women who may become pregnant, and breastfeeding women should not take this drug. While taking this drug, care must be taken as irregular meals, excessive exercise, and drug interactions can lead to hypoglycemia or lactic acidosis. Symptoms of hypoglycemia include dizziness, trembling, and cold sweat, and if these symptoms occur, sugar should be consumed immediately. This drug may affect liver and kidney function, so regular blood tests and kidney function tests should be performed before and during treatment. Especially in the elderly, kidney function may decline, so careful monitoring is essential. Alcohol consumption can increase the risk of lactic acidosis when taken with this drug, so avoid excessive drinking. If oral intake is difficult due to surgery or severe illness, temporarily discontinue this drug and resume after recovery. If blisters or severe joint pain occur while taking this drug, inform a doctor immediately and discontinue use if necessary. In case of overdose, visit a medical institution immediately for proper treatment, as this drug can be partially removed through hemodialysis. While taking this drug, regular meals, exercise, and periodic blood sugar and kidney function tests are very important.

Serious side effects

Hives, severe allergic reactions (including anaphylaxis, angioedema), Stevens-Johnson syndrome and other exfoliative skin diseases, acute pancreatitis, difficulty breathing, acute renal failure, acute and chronic metabolic acidosis (lactic acidosis), hypoglycemia, severe and disabling joint pain, bullous pemphigoid, liver abnormalities (including jaundice), serious allergic reactions (tightness in the chest, difficulty breathing, cold sweat, pallor), acute renal failure, severe edema,

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory infection
• nasopharyngitis
• headache
• muscle pain
• limb pain
• back pain

This drug should be stored in a tightly sealed container to prevent air from entering and should be kept at a temperature between 1 and 30 degrees Celsius. This storage method helps maintain the drug's effectiveness and prevents deterioration.

Appearance

Pink oval film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)]