Janusitin M Tablet 50/1000 mg

Adult dose

This medication is generally taken twice a day with food. The dosage is gradually increased to reduce gastrointestinal adverse reactions caused by metformin. 1. For patients not currently being treated with metformin: The initial dosage is 1 tablet (50/500 mg) taken twice daily, and it can be titrated to 1 tablet (50/1000 mg) taken twice daily. 2. For patients currently being treated with metformin: Recommendation for initial dosage is sitagliptin at 50 mg, taken twice daily (total 100 mg) along with the patient's existing metformin dosage.

This medication contains both sitagliptin and metformin and is used for diabetes treatment. When taking this medication, serious allergic reactions may occur, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck appear, discontinue use immediately and consult a physician. There is also a risk of acute pancreatitis, which is inflammation of the pancreas; therefore, if abdominal pain, vomiting, or nausea occur after taking this medication, immediately inform healthcare professionals. Patients with significantly reduced kidney function or conditions that may affect kidney function, such as heart failure, acute myocardial infarction, or severe infections, should not use this medication. It is also unsafe for women who are pregnant or may become pregnant, as well as for breastfeeding women. This medication may lead to a rare but serious side effect called lactic acidosis, so it is important to undergo regular kidney function tests and blood tests. If dehydration, severe vomiting, or diarrhea occurs, stop taking the medication. Care should be taken as hypoglycemia may occur in individuals with high levels of physical activity, irregular eating patterns, or those taking other blood sugar lowering agents. Alcohol consumption should be avoided while taking this medication, and it should be temporarily discontinued prior to any scheduled surgeries, confirming that kidney function is normal before resuming. Additionally, because this medication may interact with other drugs, inform healthcare professionals of any other medications being taken. Elderly patients should exercise more caution as kidney function may decline, and regular kidney function tests should be conducted. It is important to immediately consult a physician if any unusual symptoms or suspected side effects occur.

Serious side effects

Hives, severe hypersensitivity reactions (anaphylaxis, angioedema, Stevens-Johnson syndrome), severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, acute pancreatitis, acute renal failure, difficulty breathing, respiratory problems, jaundice of the skin or eyes, liver abnormalities, sudden and severe headaches, confusion, vision changes, paralysis, severe swelling, acute renal failure, high blood pressure, abdominal pain, dizziness, unstable angina.

Mild side effects

Diarrhea, upper respiratory tract infection, headache, nausea, vomiting, abdominal pain, rhinitis, constipation, muscle pain, limb pain, back pain, pruritus, thrombocytopenia, decreased appetite, itching, dizziness, hypoglycemia, and joint pain with severity and disability.

This medication should be stored in a tightly sealed container to prevent air exposure, at room temperature between 1°C and 30°C. Proper storage will maintain the drug's effectiveness and allow for safe use.

Appearance

Pink oval film-coated tablet

Package unit

30 tablets/box[(10 tablets/PTP x 3)]