Ambildagliptin 50 mg (Dapagliflozin)

Adult dose

This medication can be administered alone or in combination with metformin when prior diabetes medication therapy has not been experienced, at a dose of 50 mg once daily in the morning or 100 mg divided into 50 mg twice daily (morning and evening). If sufficient blood sugar control is not achievable with monotherapy using metformin or thiazolidinedione, the recommended dose for this drug used in combination is 100 mg daily, divided into 50 mg doses twice daily in the morning.

This medication should not be used in patients with allergies to the active ingredient or other ingredients. It should also not be administered to patients with type 1 diabetes or diabetic ketoacidosis. Since it contains lactose, patients with lactose intolerance or related genetic issues should avoid use. This drug can cause liver dysfunction; therefore, regular liver function tests should be conducted before and during treatment. If liver function levels rise to more than three times the upper limit of normal, treatment should be discontinued. There is a risk of acute pancreatitis; thus, if symptoms of pancreatitis appear, the use of this medication should be stopped immediately. As there is a risk of hypoglycemia, caution is needed when used, particularly with sulfonylurea drugs. Symptoms such as dizziness or headaches may occur, so care should be taken when driving or operating machinery. If there are severe joint pain or abnormal skin symptoms such as blisters, ulcers, etc., you should consult a physician immediately. Pregnant or breastfeeding women should avoid using this medication, and it is not recommended for children under 18. Use should be cautious in patients with end-stage renal disease, and no dose adjustment is required for the elderly. In cases of overdose, since there is no specific antidote, symptomatic supportive treatment is necessary. Store away from children, and do not transfer to another container.

Serious side effects

Hives, angioedema, chest tightness, difficulty breathing, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, yellowing of the skin or eyes (jaundice), hepatitis, liver dysfunction, sudden and severe headaches, seizures, confusion, visual disturbances, paralysis, severe swelling, significantly reduced urine output, acute myocardial infarction, nodular arrhythmias, acute cholecystitis, pneumothorax, cholelithiasis, femoral fractures, peripheral artery disease.

Mild side effects

• Headache
• dizziness
• tremors
• fatigue
• nausea
• constipation
• weakness
• weight gain
• blood sugar decrease
• gastroesophageal reflux

This medication should be stored in a tightly sealed container to protect it from air and moisture, preferably in a cool place below 30 degrees Celsius. Proper storage helps maintain the drug's efficacy over time.

Appearance

White to pale yellow circular tablet

Package unit

28 tablets/box [14 tablets/PTP (x2)]