Dapagliflozin and Sitagliptin Tablets 10/100 mg

Adult dosage

For patients receiving sitagliptin 100 mg and dapagliflozin 10 mg, one tablet may be administered once daily, regardless of meal times. The tablet should be swallowed whole.

This medication contains the active ingredients sitagliptin and dapagliflozin, which are used in the treatment of diabetes. First, this medication may cause hypersensitivity reactions, so it must be discontinued immediately if allergic reactions occur. Caution is especially needed as anaphylaxis, angioedema, and serious skin conditions may arise. Additionally, acute pancreatitis has been reported rarely, so if abdominal pain, vomiting, or other symptoms occur, consult a doctor immediately. This medication should not be used in patients with type 1 diabetes or those undergoing dialysis, and patients with impaired renal function may require dose adjustment. The dapagliflozin component may induce decreased fluid volume and hypotension; therefore, elderly patients and those taking diuretics should have their blood pressure and fluid status monitored regularly. There may be an increased risk of hypoglycemia when used in conjunction with insulin or sulfonylureas for blood sugar control, necessitating dose adjustment. This medication may increase the risk of genital infections and urinary tract infections, so appropriate treatment should be obtained if infection symptoms appear. It is recommended that women who are pregnant or breastfeeding do not use this medication, and safety in children under 18 years has not been established. There is no specific antidote for overdose, so appropriate treatment should be administered based on symptoms, and some components may be removed by dialysis. There is a risk of hypoglycemia when driving or operating machinery, so caution is advised. Finally, this medication should be stored in its original container, out of reach of children.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, anaphylaxis, angioedema, Stevens-Johnson syndrome, rash, blisters, skin peeling, pain in oral/ocular mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, cough with fever respiratory anomalies, yellowing of skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and severe

Mild side effects

• Headache
• nasopharyngitis
• upper respiratory infection
• diarrhea
• vomiting
• dizziness
• constipation
• thirst
• hypoglycemia
• back pain

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius. This will ensure the medication's effectiveness is preserved safely.

Appearance

Bright yellow rectangular film-coated tablets

Package unit

Box - 28 tablets/box [(7 tablets/PTP (Alu-Alu) x 4)], Box - 30 tablets/box [(10 tablets/PTP (Alu-Alu) x 3)]