Posibis Tablets 10/100 mg

Adult dosage

This medication can be administered once daily, regardless of meals, for patients receiving 100 mg of sitagliptin and 10 mg of dapagliflozin, with 1 tablet to be swallowed whole.

This medication contains sitagliptin and dapagliflozin and is used for the treatment of diabetes. First, during the use of this medication, severe allergic reactions, such as anaphylaxis or severe skin rashes, may occur, so if these symptoms appear, discontinue the medication immediately and consult a physician. Additionally, this medication may cause pancreatitis, which is a severe side effect involving inflammation of the pancreas, so if symptoms such as abdominal pain, nausea, or vomiting occur after administration, inform medical personnel immediately. This medication is not for use in patients with type 1 diabetes, diabetic ketoacidosis, or patients undergoing dialysis. Particularly, patients with poor kidney function, elderly patients, and those on diuretics should have their body fluid status and kidney function monitored regularly while using this medication, and caution should be exercised to avoid symptoms of hypotension. This medication may increase the risk of genital infections or urinary tract infections; therefore, immediate treatment should be sought if symptoms of infection appear. Also, this medication may cause hypoglycemia, so particularly if taken with insulin or sulfonylureas, blood sugar should be checked frequently, and attention should be paid to hypoglycemic symptoms. It is recommended that pregnant or breastfeeding women do not use this medication, and if pregnancy is planned or discovered, medical personnel should be consulted. The safety and efficacy in children and adolescents under 18 years of age have not been established, so it should not be used. In the case of overdose, prompt medical attention should be sought for appropriate treatment; while some components may be removed by hemodialysis, there is no standard detoxification method. Lastly, this medication should be stored out of the reach of children and kept in its original container to maintain its quality.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, anaphylaxis, angioedema, Stevens-Johnson syndrome, exfoliative skin disease, acute pancreatitis, fatal hemorrhagic or necrotizing pancreatitis, acute kidney injury, worsening of kidney function, diabetic ketoacidosis, ketosis, urosepsis, pyelonephritis, severe rash, blisters, skin peeling, pain in mouth/eye mucosa, severe dermatological reactions, respiratory distress,

Mild side effects

• Upper respiratory tract infection
• nasopharyngitis
• headache
• diarrhea
• dry mouth
• constipation
• back pain
• dysuria
• polyuria
• nocturia

This medication should be stored in a tightly sealed container to protect it from air and moisture. The recommended storage temperature is room temperature between 1 degree and 30 degrees. Proper storage will help maintain the medication's efficacy for an extended period.

Appearance

Bright yellow film-coated tablet in a rectangular shape

Package unit

30 tablets/box [10 tablets/Alu-Alu × 3]