Sitaren Duo Tablet 50/850 mg

Adult dose

This medication is generally taken in two doses daily with meals, and the dosage should be gradually increased to reduce gastrointestinal adverse effects related to metformin. 1. For patients not currently treated with metformin: Take this drug 50/500 mg twice daily, one tablet at a time, and it can be increased to 50/1000 mg twice daily, one tablet each time. 2. For patients currently treated with metformin:

This medication is used in the treatment of diabetes. During treatment, allergic reactions may occur; therefore, if symptoms such as rash, hives, or shortness of breath develop, treatment should be stopped immediately, and a doctor should be consulted. Serious inflammation of the pancreas, known as pancreatitis, may occur, so it is important to inform healthcare professionals if symptoms such as abdominal pain, nausea, or vomiting develop. Patients with impaired kidney function or those with serious infections, dehydration, or heart failure should not take this medication, and it should be temporarily stopped before and after surgery. It is safer for pregnant or breastfeeding women to avoid taking this medication. This medication can cause hypoglycemia; thus, care should be taken during periods of missed meals or sudden increases in physical activity, and the risk of hypoglycemia may increase when taken together with other hypoglycemic agents. Regular testing and monitoring are necessary for patients with impaired liver or kidney function, especially the elderly should be cautious of decreased kidney function. Alcohol consumption or excessive alcohol intake may increase the risk of side effects from this drug, so it should be avoided. If severe joint pain or blisters occur, a doctor should be consulted immediately. Drug interactions may occur, so other medications being taken should be reported to health care providers. In case of overdose, it is important to visit a medical facility immediately for proper treatment, and the medication may be removed through blood dialysis.

Serious side effects

Hives, severe hypersensitivity reactions (anaphylaxis, angioedema, Stevens-Johnson syndrome, exfoliative dermatitis), acute pancreatitis (including hemorrhagic or necrotizing), severe lactic acidosis, hypoglycemia, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, difficulty breathing, breathing difficulties, or asthma attacks, liver abnormalities (jaundice and general malaise), serious neurological symptoms (sudden and severe headache, lightning)

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory infection
• nasopharyngitis
• headache
• muscle pain
• limb pain
• back pain

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature of between 1 to 30 degrees Celsius to preserve the medication's efficacy and safety for a long period.

Appearance

Pink oval film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP×3)]