Rabenu Tablet 10/500 mg (Rabeprazole Sodium, Sodium Bicarbonate)

Adult dose

1) Gastric ulcer, duodenal ulcer: Typically, 10/500mg is administered orally once daily to adults. Depending on symptoms, 20/500mg may be taken orally once daily. Typically, treatment lasts for up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. 2) Erosive or ulcerative gastroesophageal reflux disease: 10/500mg or 20/500mg is administered once daily for 4 to 8 weeks. If the condition does not improve after 8 weeks of proton pump inhibitor (PPI) treatment, an additional 8-week course of 10/500mg or 20/500mg may be administered orally twice daily. However, the 20/500mg two times daily is only for those patients with confirmed severe mucosal damage. 3) Relief of symptoms of gastroesophageal reflux disease: Administer 10/500mg once daily. If symptoms are not controlled after 4 weeks, further evaluation is necessary. Once symptoms resolve, on-demand therapy with 10/500mg once daily can be used to manage any subsequent symptoms as needed. 4) Long-term maintenance therapy for gastroesophageal reflux disease: Administer orally 10/500mg or 20/500mg once daily, depending on the patient. 2. For liver impaired patients: Adverse reactions of hepatic encephalopathy have been reported in cirrhotic patients; therefore, it should be administered with caution. 3. For elderly patients: Use is cautious as they often have impaired liver function. 4. For children: Safety for children has not been established.

Child dose

Safety for children has not been established.

This medication should not be used in certain patients. For example, it should not be administered to pregnant or breastfeeding women who are allergic to this medication or its components, or those taking certain antiviral medications. Patients with liver or kidney dysfunction, elderly patients, and patients with heart or lung issues should use this medication cautiously. Patients requiring restrictions on sodium intake or with electrolyte imbalances also need to be careful. Various side effects may occur while taking this medication, such as skin rash, itching, blood abnormalities, liver function abnormalities, heart problems, gastrointestinal symptoms, neurological symptoms, respiratory symptoms, muscle or joint pain, so if any symptoms arise, immediate consultation with healthcare professionals is necessary. Regular blood tests and liver function tests are required with long-term use, and side effects like osteoporosis or hypomagnesemia may occur, so caution is advised. This medication inhibits stomach acid secretion, which may slightly increase the risk of gastrointestinal infections, so patients should inform healthcare professionals if diarrhea persists. While this medication does not significantly impact driving or machine operation, caution is advised as drowsiness may occur. It may interact with other medications, so it is essential to inform doctors or pharmacists about any concurrent medications, especially when combined with certain antiviral agents or anticoagulants. Pregnant or breastfeeding women should refrain from taking this medication, and elderly patients may be at higher risk for side effects due to impaired liver function, so use should be cautious. This medication should not be chewed or crushed, but swallowed whole in its tablet form and stored out of reach of children.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory problems with cough+fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urine

Mild side effects

• Rash
• itching
• diarrhea
• constipation
• abdominal pain
• bloating
• dyspepsia
• belching
• nausea
• dry mouth

This medication should be kept in a tightly sealed container to protect it from exposure to air or moisture, and should be stored at room temperature between 1 to 30 degrees Celsius. Storing it this way will help maintain the drug's effectiveness for a longer period.

Appearance

Light brownish-yellow oval film-coated tablet

Package unit

Bottle - 28 tablets/bottle