Samsita Plus Tablet 50/500 mg

Adult dose

This medication is generally taken twice a day with food, and the dosage may be gradually increased to reduce gastrointestinal side effects from metformin. 1. Patients not currently receiving metformin: Take one tablet of this medication 50/500 mg twice daily; it can be increased to 50/1000 mg, one tablet twice daily. 2. Patients receiving metformin:

This medication contains sitagliptin and metformin, which are used for diabetes treatment. Severe allergic reactions may occur while taking this medication, so if you experience symptoms such as rash, hives, difficulty breathing, or swelling of the face or neck, you should immediately discontinue use and consult a physician. Acute pancreatitis, a serious inflammation of the pancreas, can occur rarely; therefore, if you experience abdominal pain, nausea, vomiting, or fever, you should quickly notify medical personnel. The metformin component in this medication can cause a rare but serious condition called lactic acidosis; if you experience sudden fatigue, muscle pain, difficulty breathing, or abdominal pain, you should immediately visit a hospital. Patients with impaired kidney function or conditions that affect the kidneys, such as dehydration, severe infections, heart failure, or acute myocardial infarction, should not take this medication. Additionally, if you are undergoing imaging tests using iodine contrast agents, you must discontinue taking this medication for a certain period before and after the test, and resume only after confirming that kidney function is normal. It is advisable not to use this medication in pregnant or nursing women, or in children and adolescents under 18 years of age, as its safety has not been established in these populations. During the use of this medication, it is important to maintain regular meals and exercise, as well as regularly monitor blood sugar and kidney function to ensure there are no abnormalities. You should be alert for symptoms of hypoglycemia, especially if taking insulin or other hypoglycemic agents, as the risk of hypoglycemia may increase, necessitating observation of symptoms and consultation with a doctor to adjust the medication dosage if necessary. In case of overdose, you should immediately go to the hospital for appropriate treatment; some components may be removed by dialysis. You should avoid excessive alcohol intake while taking this medication, and patients with liver or kidney dysfunction should be particularly cautious. Additionally, if severe joint pain or skin blisters occur, you should immediately inform medical personnel. This medication may interact with various other medications, so be sure to inform your doctor or pharmacist of any other medications you are taking.

Serious side effects

Hives, angioedema, chest tightness, difficulty breathing, anaphylaxis, Stevens-Johnson syndrome, severe allergic reactions, severe rash, blisters, skin peeling, mucosal pain in the mouth/eyes, severe skin adverse reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities accompanied by cough and fever, respiratory problems, jaundice (yellowing of the skin or eyes), profound lethargy, liver abnormalities (jaundice), sudden

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory infection
• nasopharyngitis
• headache
• hypoglycemia
• constipation
• muscle pain

This medication should be stored in a tightly closed container that does not allow air to pass through, at a temperature between 1 degree and 30 degrees Celsius. Storing it this way will help maintain the effectiveness of the medication and prevent degradation.

Appearance

Light pink oval film-coated tablet

Package unit

30 tablets/box[(10 tablets/PTP×3)]