Medication info

Gontheon Injection 1200mg (Reduced Glutathione)

Prescription medicationInjections근육 · 정맥
Ingredient · strength
Glutathione (Reduced)›1200mg / 1 vial
Manufacturer / importer
건일바이오팜주식회사
Appearance
An injection containing a white porous solid in a colorless transparent vial
Packaging
1 vial x 10
Approval status
Active

MFDS item code 202107482 · Notified 2021.11.15

Summary

Main use
Prevention of cisplatin-induced neurotoxicity
Who receives it
Adults
Adult administration
In severe cases, administer 600-1200mg by intramuscular injection or intravenous drip daily. In cases of treatment over several days or mild cases, administer 300-600mg by intramuscular injection or intravenous drip daily.

Ingredients

Manufacturer
건일바이오팜주식회사

Efficacy & effects

Prevention of cisplatin-induced neurotoxicity

  • Neurotoxicity
View approved original text

This medication helps prevent neurotoxicities that can occur with the use of cisplatin and similar chemotherapy drugs. These drugs are used to reduce the risk of nerve damage in patients, protect nerve function during treatment, and improve the quality of life for patients.

How it is given

Adult administration

In severe cases, administer 600-1200mg by intramuscular injection or intravenous drip daily. In cases of treatment over several days or mild cases, administer 300-600mg by intramuscular injection or intravenous drip daily.

Precautions

This medication may rarely cause severe allergic reactions such as anaphylaxis, so the patient's condition should be closely monitored during administration. If symptoms such as facial pallor, low blood pressure, or irregular pulse appear, administration should be stopped immediately. Additionally, rare hypersensitivity reactions such as skin rashes may occur, and if these symptoms appear, use of the drug should be halted. Gastrointestinal symptoms may include loss of appetite, nausea, vomiting, or abdominal pain; if these symptoms occur, the healthcare provider should be informed. This medication should be reconstituted and administered immediately prior to use, as any delay after reconstitution may reduce its efficacy. When administering an intramuscular injection, care should be taken to avoid nerves or blood vessels, and if multiple injections are necessary, they should be given at alternating sites rather than repeatedly in the same area. Particular caution should be taken when administering this medication to children and minors. This medication should be stored in a safe place out of reach of children and must be kept in its original container with the lid tightly closed to prevent misuse or quality degradation.

Side effects and when to seek care immediately

Serious side effects

Symptoms of anaphylaxis

Mild side effects

  • Facial pallor
  • low blood pressure
  • abnormal pulse
  • rash
  • loss of appetite
  • nausea
  • vomiting
  • abdominal pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent air ingress, ideally at room temperature between 1°C and 30°C. Proper storage will maintain the drug's effectiveness and prevent degradation.

Appearance and packaging

Appearance

An injection containing a white porous solid in a colorless transparent vial

Package unit

1 vial x 10

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.