Exiglumem Sustained-release Tablet 5/1000 mg

Adult dose

The dosage of this medication should be individualized based on the patient's current treatment regimen, efficacy, and tolerability, and should not exceed the maximum recommended dose of dapagliflozin 10 mg and sustained-release metformin 2000 mg. This medication is generally administered once daily with the evening meal. The maximum dose is once daily dapagliflozin 10 mg/sustained-release metformin 2000 mg, taking 2 tablets of 5 mg/1000 mg.

This medication helps control blood sugar; however, it can very rarely cause a serious condition called lactic acidosis, so caution is needed. When taken with other diabetes medications, there can be a risk of hypoglycemia. This drug should not be administered to certain patients. For example, patients with an allergy to its components, those with moderate to severe renal impairment, dehydrated or severely infected patients, patients with type 1 diabetes, and pregnant or breastfeeding women should not take it. Moreover, patients about to undergo surgery or scheduled for tests using contrast agents should discontinue this medication for a certain period. Patients with slightly reduced renal function or those who are dehydrated should use this medication with caution and carefully monitor for hypotension or changes in renal function. Particularly elderly patients or those taking diuretics need to exercise additional caution. Common side effects while taking this medication include genital infections, urinary tract infections, hypoglycemia, dehydration symptoms, dizziness, and dry mouth. Additionally, serious side effects such as ketoacidosis or acute kidney injury may occur rarely, so if any abnormal symptoms arise, prompt consultation with a physician is required. This medication is not recommended for patients with impaired liver function, and alcohol intake should be avoided. Moreover, if blood sugar control fails or an acute condition develops, temporary discontinuation of the medication and appropriate treatment should be administered. Pregnant or breastfeeding women should not take this medication, and safety in pediatric patients has not been established. This medication may interact with other drugs, so particularly when used with diuretics, insulin, or sulfonylureas, dose adjustments may be necessary to reduce the risk of hypoglycemia or dehydration. In the event of an overdose, immediate visit to a medical institution is required for appropriate treatment, and while this medication has minimal impact on driving or operating machinery, dizziness may occur, so caution is advised. Lastly, this medication should be kept out of reach of children and stored in its original container to maintain quality.

Serious side effects

Lactic acidosis, severe hypoglycemia, acute kidney injury, renal impairment, diabetic ketoacidosis, urosepsis, pyelonephritis, perineal necrosis, Guillain-Barré syndrome, bacterial pneumonia, acute cholecystitis, atrial fibrillation, severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness), severe skin adverse reactions (severe rash, blisters, skin peeling with high fever, mucosal pain in the mouth/eyes), respiratory problems (difficulty breathing, ...

Mild side effects

• Vulvitis
• balanitis and related genital infections
• urinary tract infections
• fungal infections
• hypoglycemia
• thirst
• dizziness
• constipation
• dry mouth
• back pain

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness over time.

Appearance

Pink to dark pink oval sustained-release film-coated tablets, convex on both sides

Package unit

10 tablets/box [10 tablets/PTP x 1], 30 tablets/bottle, 30 tablets/box [10 tablets/PTP x 3]