S1 Duo Tablet 20/800 mg
Esomeprazole Magnesium Trihydrate 22.26mg · Sodium Bicarbonate 650mg
Tablet · Prescription medication · Combination
Wonkwang Pharmaceutical Co., Ltd.
MFDS item code 202107429 · Approved 2021.11.11
Treatment and prevention of reflux esophagitis, alleviation of symptoms of gastroesophageal reflux disease
This medication is effective for the treatment of gastroesophageal reflux disease, especially erosive reflux esophagitis. It is also used for long-term maintenance therapy to prevent recurrence in patients with esophagitis. It helps alleviate symptoms of gastroesophageal reflux disease that do not involve esophagitis. This is a drug effective in improving various symptoms and conditions related to gastroesophageal reflux.
This medication should be taken on an empty stomach at least 1 hour before meals. Swallow the tablet whole with at least half a cup of water. Do not use other beverages. Do not chew or crush the tablet. - Treatment of erosive reflux esophagitis: Administer 40/800 mg once daily for 4 weeks. - If symptoms persist or do not improve, an additional 4 weeks of treatment may be required. - Maintenance therapy to prevent recurrence: 20/800 mg once daily.
This medication should not be used in certain patients. For example, patients with allergies or hypersensitivity to this medication or its components, those taking certain antiviral agents, nursing mothers, and patients with a history of myocardial infarction should not be treated with this drug. Patients with liver or kidney problems, elderly individuals, those with impaired heart or lung function, and patients with severe gastrointestinal ulcers should use this drug cautiously. Patients with electrolyte imbalances or those who need to restrict sodium intake should also exercise caution. This medication can cause various side effects. Common side effects include headache, abdominal pain, diarrhea, nausea, and vomiting, while rare but serious reactions may include blood abnormalities, liver dysfunction, skin rashes, myalgia, and nephritis. Prolonged use may increase the risk of hypomagnesemia or fractures, necessitating regular monitoring. This medication may interact with other drugs; thus, it should be carefully monitored when used with anticoagulants, antidepressants, anticonvulsants, and antiviral agents, following medical advice. Some interactions may prohibit concurrent use or require dosage adjustments. Due to limited safety data during pregnancy, this medication should be administered cautiously under medical guidance if necessary, and it is generally not recommended for nursing mothers. In case of overdose, no specific antidote exists, and appropriate treatment and monitoring are needed based on symptoms. This medication should be kept out of reach of children, and transferring it to other containers should be avoided to maintain quality.
Urticaria, angioedema, anaphylactic reactions, shock, hyponatremia, hypomagnesemia, hypocalcemia, mental confusion, jaundice, hepatitis, hepatic failure, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), interstitial nephritis, gynecomastia, rhabdomyolysis, severe edema, severe allergic reactions
Not everyone experiences these, and they can vary from person to person.
This medication should be stored in a tightly closed container to protect it from air and moisture. The appropriate storage temperature is room temperature between 1 to 30 degrees Celsius.
Light pink oval film-coated tablet
30 tablets/bottle
Even with the same ingredient, strength, dosage form and how it is taken can differ.
Esomeprazole Magnesium Trihydrate 22.26mg · Sodium Bicarbonate 650mg
Tablet · Prescription medication · Combination
Wonkwang Pharmaceutical Co., Ltd.
CombinationEsomeprazole Magnesium Trihydrate 22.26mg · Sodium Bicarbonate 800mg
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CTC Bio, Co., Ltd.
CombinationEsomeprazole Magnesium Trihydrate 22.26mg · Sodium Bicarbonate 800mg
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Mothers Pharmaceutical Co., Ltd.
CombinationEsomeprazole Magnesium Trihydrate 22.26mg · Sodium Bicarbonate 800mg
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Pharmgen Science Co., Ltd.
CombinationEsomeprazole Magnesium Trihydrate 22.26mg · Sodium Bicarbonate 800mg
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Teragen Etex Co., Ltd.
CombinationEsomeprazole Magnesium Trihydrate 22.26mg · Sodium Bicarbonate 800mg
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Samjin Pharmaceutical Co., Ltd.
CombinationEsomeprazole Magnesium Trihydrate 22.26mg · Sodium Bicarbonate 800mg
Tablet · Prescription medication · Combination
Ahn-Guk Pharmaceutical Co., Ltd.
CombinationEsomeprazole Magnesium Trihydrate 22.26mg · Sodium Bicarbonate 800mg
Tablet · Prescription medication · Combination
Hana Pharmaceutical Co., Ltd.
Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.
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For anything that needs medical judgment, consult a doctor or pharmacist.
This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.