Medication info

Nexium Tablet 20/800 milligrams

Prescription medicationTablet경구
Ingredient · strength
Esomeprazole Magnesium Trihydrate›22.26mg / 1 tabletSodium Bicarbonate›650mg / 1 tablet
Manufacturer / importer
(주)제뉴파마
Appearance
Pale pink oval film-coated tablet
Packaging
30 tablets per bottle
Approval status
Active

MFDS item code 202107331 · Approved 2021.11.04

Summary

Main use
Treatment and prevention of erosive reflux esophagitis, alleviation of symptoms of gastroesophageal reflux disease
Who takes it
Adults
Adult dose
This drug should be taken at least 1 hour before meals on an empty stomach. Swallow it whole with at least half a glass of water. Do not take with any beverages other than water. This drug should not be chewed or crushed. 1. Adults - Treatment of erosive reflux esophagitis: administer 40/800mg once daily for 4 weeks. - In case esophagitis is untreated or symptoms persist, continue taking for an additional 4 weeks.

Ingredients

Manufacturer
(주)제뉴파마

Efficacy & effects

Treatment and prevention of erosive reflux esophagitis, alleviation of symptoms of gastroesophageal reflux disease

  • Gastroesophageal reflux disease
  • erosive reflux esophagitis
  • esophagitis
  • symptoms of gastroesophageal reflux disease
View approved original text

This medication is used to treat gastroesophageal reflux disease, particularly erosive reflux esophagitis. It is also effective for long-term maintenance therapy to prevent recurrence in patients with esophagitis. It helps alleviate symptoms associated with gastroesophageal reflux disease even in the absence of esophagitis. This drug improves symptoms by regulating gastric acid secretion and protects the esophageal mucosa, thus reducing recurrence. It plays an important role in maintaining the health of your stomach and esophagus, so you can take it with peace of mind. Therefore, this medication is used for improving gastroesophageal reflux disease.

How to take

Adult dose

This drug should be taken at least 1 hour before meals on an empty stomach. Swallow it whole with at least half a glass of water. Do not take with any beverages other than water. This drug should not be chewed or crushed. 1. Adults - Treatment of erosive reflux esophagitis: administer 40/800mg once daily for 4 weeks. - In case esophagitis is untreated or symptoms persist, continue taking for an additional 4 weeks.

Precautions

This drug should not be used by individuals who are allergic to this medication or have previously experienced hypersensitivity to its ingredients. Patients taking certain antiviral drugs such as atazanavir, nelfinavir, and rilpivirine should not use this medication as it may cause side effects or reduce effectiveness. Women who are nursing should avoid taking this drug. Patients with a history of myocardial infarction or currently suffering from it should also avoid this drug. Patients with liver or kidney function problems, the elderly, and individuals with weakened heart or lung function should use this drug with caution, and special care is required in cases of severe gastrointestinal ulcers. Patients with electrolyte imbalances or those who need to limit sodium intake must take special precautions while taking this drug. This medication can cause various side effects, including gastrointestinal symptoms such as headache, abdominal pain, diarrhea, nausea, and vomiting, as well as skin rashes, itching, and, rarely, serious allergic reactions or blood abnormalities, muscle weakness. Particularly with long-term use, there may be electrolyte abnormalities such as hypomagnesemia, so regular testing is required. Since this drug suppresses gastric acid, it can increase the risk of certain bacterial infections, and prolonged use may lead to an increased risk of fractures. This drug has a high potential for interactions with other medications, so if you are taking other drugs, you must consult with your doctor or pharmacist. The safety of this drug during pregnancy has not been sufficiently verified, so it should be used carefully, and breastfeeding individuals should avoid taking it. There are no specific antidotes for overdose, so appropriate treatment must be received based on symptoms. Finally, keep this medication out of the reach of children, do not transfer it to other containers, and always follow the instructions of your doctor or pharmacist before use.

Side effects and when to seek care immediately

Serious side effects

Angioedema, anaphylaxis/shock, urticaria, severe rash with fever, blisters, skin peeling, pain of mucous membranes of the mouth/eyes, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms, shortness of breath or difficulty breathing, asthmatic attacks, respiratory abnormalities with cough and fever, jaundice, liver failure, sudden and severe

Mild side effects

  • Leukopenia
  • thrombocytopenia
  • fever
  • peripheral edema
  • hyponatremia
  • hypomagnesemia
  • insomnia
  • agitation
  • confusion
  • depression
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  • aggression
  • hallucinations
  • headache
  • dizziness
  • sensory changes
  • drowsiness
  • taste disturbance
  • blurred vision
  • bronchospasm
  • pancreatitis
  • abdominal pain
  • constipation
  • diarrhea
  • abdominal bloating
  • nausea
  • vomiting
  • dry mouth
  • stomatitis
  • gastrointestinal candidiasis
  • microscopic colitis
  • increased liver enzymes
  • hepatitis
  • dermatitis
  • itching
  • rash
  • alopecia

Not everyone experiences these, and they can vary from person to person.

Storage

This drug must be stored in a tightly sealed container to protect it from air and moisture, and the storage temperature should be maintained between 1 degree and 30 degrees Celsius at room temperature. Thus, it is important to avoid direct sunlight, high temperatures, and humid places for storage.

Appearance and packaging

Appearance

Pale pink oval film-coated tablet

Package unit

30 tablets per bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.