M-Stein 100 mg (Sildenafil Citrate)

Adult dose

As sildenafil, the recommended dose is 25 to 50 mg taken orally approximately 1 hour before sexual activity, once daily. It can be administered any time from 4 hours to 30 minutes before sexual activity. The dosage may be adjusted based on efficacy and tolerability.

This drug has a vasodilating effect, which may lower blood pressure; therefore, taking it with nitrates or NO donors can pose a risk of excessively lowering blood pressure. Patients with heart or vascular issues should carefully assess their condition before using this drug, and sexual activity is not recommended for patients with severe cardiovascular disease; thus, this drug should not be used in such cases. This drug can temporarily lower blood pressure, so caution is especially needed during sexual activity for patients with underlying cardiovascular conditions. Patents with serious heart rhythm problems, heart failure, unstable angina, very low or very high blood pressure, and pigmentary retinopathy should not use this drug. If an erection lasts longer than 4 hours, the patient should seek medical attention immediately, as untreated cases can lead to penile tissue damage and loss of erectile function. Patients with specific heart valve diseases or compromised blood pressure regulation may be sensitive to this drug and should take caution. The blood concentration of this drug can significantly increase when taken with certain medications like Ritonavir, heightening the risk of side effects; therefore, patients on such medications may need dosage adjustments. Formulations containing aspartame should not be given to patients with phenylketonuria, and aspartame intake should also be limited. This drug should not be used by individuals who are allergic to it or are on regular nitrate therapy, patients with severe cardiovascular diseases who should not engage in sexual activity, patients with severe liver failure, patients with hypotension or uncontrolled hypertension, individuals with a recent history of cardiovascular accidents, those with pigmentary retinopathy, patients currently taking other treatments for erectile dysfunction, or individuals under the age of 18 and women. Patients with penile deformities, bleeding disorders, the elderly, those with severe kidney failure, liver failure, or taking CYP3A4 inhibitors should use this drug cautiously, and particularly the elderly or those with reduced kidney and liver function should start at a lower dose for safety. Common side effects of this drug include headache, facial flushing, dyspepsia, dizziness, visual disturbances, nasal congestion, drowsiness, nausea, vomiting, diarrhea, visual abnormalities (temporary altered color perception, increased light sensitivity, blurred vision), rhinitis, throat discomfort, dry mouth, eye redness, eye pain, dry eyes, eye fatigue, eyelid swelling, vasodilation, tachycardia, palpitations, myalgia, limb pain, rash, itching, sweating, skin dryness, nasal bleeding, epistaxis, sinus congestion, rhinitis, pharyngitis, and asthma. Sexual activity can impose a burden on the heart, so the heart condition should be well assessed before starting this drug; if uncomfortable symptoms occur during sexual activity, it should be stopped immediately and the doctor should be consulted. Caution is needed when driving or operating machinery as dizziness or visual disturbances may occur. This drug may pose risks if taken with other erectile dysfunction treatments or certain cardiac medications, so consulting a doctor is essential. In case of overdose, symptoms may worsen, so the recommended dosage should be followed, and if abnormal symptoms appear, the patient should visit a healthcare facility immediately. This drug should be kept out of reach of children and care should be taken to not transfer it to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness (severe allergic reaction), severe rash with high fever, blisters, peeling skin, pain of mucous membranes in mouth/eyes (severe skin abnormal response), shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, skin or eyes turning yellow (jaundice), extreme lethargy (liver dysfunction), sudden and severe headache

Mild side effects

Headache, flushing, dyspepsia, nasal congestion, dizziness, drowsiness, nausea, vomiting, diarrhea, visual disturbances (temporary color perception disorder, increased sensitivity to light, blurred vision), rhinitis, throat discomfort, dry mouth, eye redness, eye pain, dry eyes, eye fatigue, eyelid swelling, vasodilation, tachycardia, palpitations, myalgia, limb pain, rash, itching, sweating, skin dryness, nasal bleeding, epistaxis, sinus congestion, rhinitis, pharyngitis, asthma

This drug must be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

Green triangular film-coated tablet with rounded corners and a score line

Package unit

8 tablets/box [8 tablets/part×1], 24 tablets/box [8 tablets/part×3], 40 tablets/box [8 tablets/part×5]