Medication info
Esomeprazole Plus Tablets 40/350 mg

Esomeprazole Plus Tablets 40/350 mg

Prescription medicationTablet경구
Ingredient · strength
Esomeprazole Magnesium Trihydrate›44.5mg / 1 tabletMagnesium Hydroxide›350mg / 1 tablet
Manufacturer / importer
한미약품(주)
Appearance
Pale pink oval film-coated tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 202107076 · Approved 2021.10.22 · Insurance code 643508490

Summary

Main use
Treatment and prevention of reflux esophagitis, relief of symptoms of gastroesophageal reflux disease
Who takes it
Adults
Adult dose
This medication should be taken on an empty stomach at least 1 hour before meals. Swallow whole with at least half a cup of water. Do not take with any other beverages besides water. This medicine should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40/350 mg once daily for 4 weeks - Maintenance therapy to prevent recurrence after treatment of esophagitis: 40/350 mg once daily

Ingredients

Manufacturer
한미약품(주)

Efficacy & effects

Treatment and prevention of reflux esophagitis, relief of symptoms of gastroesophageal reflux disease

  • Gastroesophageal reflux disease
  • erosive esophagitis
  • esophagitis
  • symptoms of gastroesophageal reflux disease
View approved original text

This medicine is used to treat gastroesophageal reflux disease (GERD) and erosive esophagitis. It is also used in long-term maintenance therapy to prevent recurrence in patients with esophagitis. It is effective in alleviating symptoms in patients with gastroesophageal reflux disease without esophagitis. This medication reduces discomfort caused by gastric acid, protects the esophageal mucosa, and improves symptoms. Thus, it is used effectively to treat various symptoms and complications caused by gastroesophageal reflux.

How to take

Adult dose

This medication should be taken on an empty stomach at least 1 hour before meals. Swallow whole with at least half a cup of water. Do not take with any other beverages besides water. This medicine should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40/350 mg once daily for 4 weeks - Maintenance therapy to prevent recurrence after treatment of esophagitis: 40/350 mg once daily

Precautions

This medicine should not be used in certain patients. For example, it should not be administered to patients who have allergies to this drug or its ingredients, those with a history of hypersensitivity to benzimidazole class drugs, patients taking certain antiviral medications, breastfeeding women, patients with severely impaired kidney function, and those with diarrhea. Patients with weakened heart function or hypermagnesemia should use this medicine with caution. This medication can cause adverse reactions in various parts of the body including blood, nervous system, digestive system, and skin, so immediate consultation with a physician is necessary if symptoms occur. Patients taking this medication for an extended period should have regular check-ups to monitor their condition, as there may be a slight increase in the risk of gastrointestinal infections, and if diarrhea persists, medical consultation is needed. Additionally, long-term use may increase the risk of fractures, so caution is advised for patients with osteoporosis. This medication can interact with other drugs, so if you are taking other medications, it is essential to inform your doctor or pharmacist, particularly when taken with antiviral drugs, anticoagulants, and antiepileptics. It is best not to use this medication during pregnancy or breastfeeding; if it needs to be used during pregnancy, a physician's judgment is required. In cases of overdose, there is no specific antidote, so appropriate treatment should be administered according to symptoms. Keep this medicine out of reach of children, and be careful not to transfer the medicine to another container as this can adversely affect quality.

Side effects and when to seek care immediately

Serious side effects

Angioedema, anaphylaxis, shock, hypomagnesemia, hypocalcemia, hypokalemia, jaundice, hepatitis, liver failure, encephalopathy, urticaria, erythema multiforme, mucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), interstitial nephritis, Clostridium difficile-associated diarrhea, rhabdomyolysis, severe allergic reactions

Mild side effects

  • Headache
  • dizziness
  • altered sensation
  • drowsiness
  • taste disturbance
  • blurred vision
  • bronchospasm
  • abdominal pain
  • constipation
  • diarrhea
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  • abdominal bloating
  • nausea
  • vomiting
  • dry mouth
  • stomatitis
  • increased liver enzymes
  • dermatitis
  • itching
  • rash
  • hair loss
  • photosensitivity
  • fractures
  • arthralgia
  • myalgia
  • gynecomastia
  • asthenia
  • increased sweating
  • allergic reactions
  • back pain
  • chest pain
  • facial swelling
  • facial flushing
  • fatigue
  • fever
  • influenza-like syndrome
  • general edema
  • leg edema

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medicine tightly in a sealed container to prevent air or moisture from entering. Additionally, it is best to keep the medicine at a cool room temperature, specifically between 1 degree to 30 degrees Celsius.

Appearance and packaging

Appearance

Pale pink oval film-coated tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.