Y2Cerecive 100 mg Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be administered with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) As celecoxib, take 200 mg once daily, or 100 mg per dose in 2 divided doses daily. 2. Rheumatoid arthritis As celecoxib, take 100 mg or 200 mg per dose 2 times daily. 3. Ankylosing spondylitis (AS) As celecoxib, administer 200 mg once daily, or 100 mg per dose in 2 divided doses daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, another treatment option should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is 400 mg of celecoxib; if necessary, an additional 200 mg may be administered on the first day of treatment. From the second day of treatment, if necessary, the recommended dose is 200 mg per dose 2 times daily. ○ Patients with hepatic impairment In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be consulted with a doctor or pharmacist if you regularly consume more than three drinks a day, as it may increase the risk of gastrointestinal bleeding. This medication may increase the risk of serious cardiovascular events such as thrombotic events, myocardial infarction, and stroke, so it should be used only at the minimum effective dose for the shortest duration possible, and healthcare professionals must be informed immediately if cardiovascular symptoms occur. Serious gastrointestinal problems such as ulcers, bleeding, and perforation may occur, particularly in elderly patients or those with a history of gastrointestinal diseases, and should be observed carefully. This medication should not be administered to patients with specific allergies, severely impaired liver or kidney function, active peptic ulcers, heart failure, ischemic heart diseases, pregnant women, and nursing mothers. Patients with liver or kidney problems, a history of cardiovascular diseases, hypertension, or asthma should take this medication with care and be monitored closely. During use, various adverse reactions such as indigestion, headaches, dizziness, skin rash, edema, hypertension, and gastrointestinal bleeding may occur, and it is necessary to consult healthcare professionals immediately if symptoms arise. This medication is metabolized in the liver, so there may be drug interactions, particularly with drugs that inhibit or induce the liver enzyme CYP 2C9, which may require dosage adjustment when used together. Women who are pregnant or may become pregnant should not take this medication, and nursing mothers should consult healthcare professionals before taking it. This medication is not recommended for children and adolescents under 18 years of age as safety and efficacy have not been established. Elderly patients should be careful when using this medication due to the higher risk of renal, hepatic, and cardiac function decline, and dosage may need to be adjusted. Dizziness or drowsiness may occur, so it is advisable to avoid driving or operating machinery. This medication does not affect platelet function, so it cannot be used as an alternative to aspirin for thrombus prevention, and the risk of gastrointestinal bleeding may increase when taken with aspirin. Those taking this medication for a long period should regularly undergo blood tests and liver and kidney function assessments to check for abnormalities. In case of overdose, symptoms such as weakness, nausea, vomiting, gastrointestinal bleeding, and renal failure may arise, requiring immediate treatment. This medication must be stored out of reach of children and should not be transferred to another container for safety.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforations, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcers, dental diseases, duodenal ulcers, esophageal ulcers, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, headache, leg cramps, sensory loss, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergic reactions, weakness, chest pain, fluid retention, generalized edema, facial swelling, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reactions, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, female infertility, chest pain, vesicular dermatitis, nail diseases, photosensitivity reactions, dermatitis, skin dryness, increased sweating, erythema multiforme, exfoliative dermatitis, mucocutaneous syndrome, toxic epidermal necrolysis, vasculitis, acute renal failure, hyponatremia, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, elevated blood sodium, elevated blood potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, elevated NPN, increased creatinine, elevated alkaline phosphatase, weight gain, loss of appetite, elevated LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthrosis, skeletal abnormalities, myalgia, cervical strain, synovitis, tendinitis, myositis, fractures, tendon ruptures, back pain, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleed, thrombocytopathies, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, granulomatous inflammation, contact dermatitis, injection site reactions, skin papules, taste disorder, albuminuria, cystitis, hematuria, dysuria, frequent urination, kidney stones, urinary incontinence, urinary tract infections, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, hearing loss, ear anomalies, otalgia, hearing impairment, headache, dizziness, constipation, thirst, ulcerative stomatitis, gastritis, allergies, low back pain, chest pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, positive RA factor, herpes zoster, pneumonia, shortness of breath, elevated ALT, hearing impairment

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and is best kept at room temperature between 15 to 30 degrees Celsius. Proper storage can help maintain the effectiveness of the medication for a longer time.

Appearance

A white to off-white capsule filled with powder containing a blue stripe.

Package unit

30 capsules/bottle, 100 capsules/bottle