Medication info
Novesil Acid 500 Milligrams (Dovesil Calcium Hydrate)

Novesil Acid 500 Milligrams (Dovesil Calcium Hydrate)

Prescription medicationTabletOral
Ingredient · strength
Dobesilate Calcium Hydrate›500mg / 1 tablet
Manufacturer / importer
Nova M Healthcare Co., Ltd.
Appearance
White rectangular tablet
Packaging
30 tablets/bottle, 90 tablets/bottle
Approval status
Active

MFDS item code 202106994 · Approved 2021.10.19 · Insurance code 073200720

Summary

Main use
Improvement of vascular disorders (e.g., diabetic retinopathy), venous disorders (e.g., edema), and hemorrhoids
Who takes it
Adults
Adult dose
Adults: Administer the following doses of calcium dobesilate hydrate orally. Vascular damage and retinopathy: 500~1000mg daily Venous disease: 750mg daily for 1~3 weeks, followed by 500mg daily. Take after meals with plenty of fluids. The dose may be adjusted according to age and symptoms.

Ingredients

Manufacturer
Nova M Healthcare Co., Ltd.

Efficacy & effects

Improvement of vascular disorders (e.g., diabetic retinopathy), venous disorders (e.g., edema), and hemorrhoids

  • Increased capillary rupture
  • permeability disorders
  • vascular damage
  • diabetic microvascular complications
  • diabetic retinopathy
  • venous insufficiency
  • post-thrombotic syndrome
  • peripheral congestive edema
  • hemorrhoids
View approved original text

This medication is used for vascular damage associated with increased capillary rupture and permeability disorders, diabetic microvascular complications, diabetic retinopathy, venous insufficiency, post-thrombotic syndrome, peripheral congestion edema, and vascular-related conditions such as hemorrhoids.

How to take

Adult dose

Adults: Administer the following doses of calcium dobesilate hydrate orally. Vascular damage and retinopathy: 500~1000mg daily Venous disease: 750mg daily for 1~3 weeks, followed by 500mg daily. Take after meals with plenty of fluids. The dose may be adjusted according to age and symptoms.

Precautions

This medication contains Dovesil Calcium Hydrate as the main ingredient and should not be used in specific patients. First, individuals who are allergic to this medication or any of its components should not take it. It is also safe for women who are pregnant or breastfeeding not to use this medication. Furthermore, individuals with genetically related lactose intolerance should avoid taking this medication due to the lactose it contains. Patients with impaired kidney function should use this medication with caution, as its safety and efficacy have not been fully studied in these patients. Particularly, in patients with severely compromised renal function or those requiring dialysis, the dosage may need to be reduced. Patients with liver dysfunction should also be cautious when using this medication, and its therapeutic benefits should be reevaluated if liver enzymes are elevated. This medication contains sodium metabisulfite, which may cause serious allergic reactions or asthma attacks in individuals allergic to sulfites, thus caution is necessary. Such reactions may occur more commonly in asthma patients. Possible side effects during use include common occurrences of headache, abdominal pain, nausea, diarrhea, vomiting, elevated liver enzyme levels, joint pain, and muscle pain. Additionally, rarely blood-related issues or severe allergic reactions may occur, and if skin rashes, fever, or joint pain develop, treatment should be discontinued immediately, and a doctor should be consulted. If signs of high fever or infection occur during the administration of this medication, a doctor should be notified immediately, and blood tests should be conducted to check the condition. If a severe allergic reaction occurs, the medication should be stopped immediately. While no interactions with other drugs are known, since it may affect blood test results, it is important to follow testing and a physician's instructions before taking this medication.

Side effects

  • Agranulocytosis
  • neutropenia
  • leukopenia
  • skin rash
  • allergic dermatitis
  • itching
  • urticaria
  • facial edema
  • anaphylactic reaction
  • headache
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  • abdominal pain
  • nausea
  • diarrhea
  • vomiting
  • increased alanine aminotransferase
  • arthralgia
  • myalgia
  • fever
  • chills
  • lethargy
  • fatigue

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a container that does not allow light to enter as it is sensitive to light. Additionally, it is advisable to store it at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the medication's efficacy and ensure safe usage.

Appearance and packaging

Appearance

White rectangular tablet

Package unit

30 tablets/bottle, 90 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.