Y2Cerecive Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this drug should be adjusted for each patient and may be administered with or without food. ○ Adults 1. Osteoarthritis (degenerative joint disease) Take 200 mg of celecoxib once daily, or 100 mg twice daily in divided doses. 2. Rheumatoid arthritis Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS) Administer 200 mg of celecoxib once daily, or 100 mg twice daily in divided doses. If no effect is observed after 6 weeks, a dose of up to 400 mg daily may be administered. If no effect is observed after 6 weeks at 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is 400 mg of celecoxib; if needed, an additional 200 mg may be administered on the first day of treatment. From the second day onward, the recommended dose is 200 mg twice daily as needed. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be consulted with a doctor or pharmacist if taken by someone who regularly consumes more than three alcoholic drinks daily due to the risk of gastrointestinal bleeding. This medication may increase the risk of cardiovascular thrombosis, myocardial infarction, and stroke, so it should only be used at the lowest effective dose for the shortest duration possible, and any cardiovascular symptoms must be reported to healthcare professionals immediately. Serious problems such as gastrointestinal perforation, ulcers, and bleeding may occur, so particularly elderly patients or those with a history of gastrointestinal bleeding should be monitored carefully. This medication should not be given to patients with certain allergies, severe liver or kidney impairment, active peptic ulcers, cardiovascular diseases, pregnant or breastfeeding women. Patients with impaired liver or kidney function, asthma, heart failure, hypertension, or elderly patients should use this medication cautiously and require regular check-ups. Various adverse reactions such as indigestion, diarrhea, headache, dizziness, rash, hypertension, cough, etc., may occur during treatment; consult a doctor if symptoms are severe or persist. This medication may interact with other drugs, so inform any medications currently being taken, especially if using with antihypertensives, anticoagulants, antidepressants, or diuretics. Women who are pregnant or planning to become pregnant should not take this medication, and if breastfeeding, should either discontinue breastfeeding or consult a doctor if taking this medication. Elderly patients may have reduced kidney and liver function, so extra caution is needed when taking this medication, and dose adjustments may be necessary. Patients taking this medication for a long time should have regular blood tests and liver and kidney function tests; if there are abnormal findings, the medication should be discontinued. In cases of overdose, symptoms such as vomiting, lethargy, drowsiness, and gastrointestinal bleeding may occur, so immediate medical attention is necessary. This medication should be kept out of the reach of children, and it is safer not to transfer it to another container.

Gastrointestinal bleeding, cardiovascular thromboembolic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, delirium, dizziness, muscle tone increase, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmias, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, indigestion, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, frequent urination, kidney stones, urinary incontinence, urinary tract infection, visual disturbances, cataract, conjunctivitis, eye pain, glaucoma, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal impairment, acute renal failure, interstitial nephritis, headache, leg cramps, tension increase, sensory decrease, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, backache, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, septicemia, sudden death, anaphylactoid reaction, angioedema, hallucinations, epilepsy exacerbation, upper respiratory tract infection, shingles, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, ear pain, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursa, arthralgia, arthrosis, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, fractures, tendon rupture, pain in various locations, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleed, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, sialadenitis, contact dermatitis, injection site reactions, skin nodules, visual disturbances, cataract, conjunctivitis, eye pain, glaucoma, retinal artery or vein occlusion, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, menstrual disorders, chest pain, anaphylactic reactions, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, fixed drug eruption, generalized bullous fixed drug eruption, fixed drug eruption, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, menstrual disorders, female infertility

This medication should be stored in a sealed container to prevent air or moisture entry, and it is recommended to keep it at room temperature between 15 degrees and 30 degrees. Proper storage will help maintain the medication's effectiveness.

Appearance

White to light yellow powder filled in capsules with white upper and lower parts

Package unit

30 capsules/bottle, 100 capsules/bottle