Medication info
Methimazole 2.5 mg (Methimazole)

Methimazole 2.5 mg (Methimazole)

Prescription medicationTablet
Ingredient · strength
Methimazole›2.5mg / 1 tablet
Manufacturer / importer
Darim Biotech Co., Ltd.
Appearance
Green round tablets
Packaging
100 tablets/bottle
Approval status
Active

MFDS item code 202106231 · Approved 2021.08.30 · Insurance code 664602700

Summary

Main use
Treatment of hyperthyroidism
Who uses it
Adults · Children
Adult dosage
1. Adults: The initial daily dose of methimazole is 15mg for mild cases, 30-40mg for moderate cases, and 60mg for severe cases, administered orally in 3 divided doses at 8-hour intervals. As hyperthyroidism resolves, the maintenance dose is 5-15mg per day in 1-2 divided doses.
Children's dosage
2. Children: The initial daily dose of this medicine is 0.4mg/kg of body weight, administered in 3 divided doses at 8-hour intervals. As hyperthyroidism resolves, the maintenance dose is 1/2 of the initial dose.

Ingredients

Manufacturer
Darim Biotech Co., Ltd.

Efficacy & effects

Treatment of hyperthyroidism

  • Hyperthyroidism
View approved original text

This medication is used for the treatment of hyperthyroidism. It alleviates symptoms caused by excessive thyroid activity, and is also effective before and after thyroidectomy and radioactive iodine therapy. It helps regulate the patient's thyroid hormone levels, aiding in recovery to a healthy state. Consistent intake and monitoring are recommended for safe treatment. This medication is used to treat hyperthyroidism.

Dosage and Administration

Adult dosage

1. Adults: The initial daily dose of methimazole is 15mg for mild cases, 30-40mg for moderate cases, and 60mg for severe cases, administered orally in 3 divided doses at 8-hour intervals. As hyperthyroidism resolves, the maintenance dose is 5-15mg per day in 1-2 divided doses.

Children's dosage

2. Children: The initial daily dose of this medicine is 0.4mg/kg of body weight, administered in 3 divided doses at 8-hour intervals. As hyperthyroidism resolves, the maintenance dose is 1/2 of the initial dose.

Precautions

This medication should not be used in patients with severe blood disorders such as agranulocytosis, leukopenia, or thrombocytopenia. Also, patients who have had allergic reactions or hypersensitivity to this medication, nursing women, and patients with a history of acute pancreatitis should not receive it. This medication contains lactose, making it unsafe for genetically lactose intolerant patients. Patients with liver issues or pregnant women or those who could become pregnant should exercise extreme caution while using this medication. Blood tests and liver function tests should be conducted periodically, and if any abnormal signs are detected, the use of this medication should be discontinued immediately. Since this medication can alter thyroid function, regular thyroid function tests should be conducted. If symptoms such as sore throat, fever, or skin rash occur while taking this medication, medical personnel should be notified immediately. When used during pregnancy, side effects may occur in the fetus, so it must be used at the minimum dose under a doctor's instruction. Nursing women should avoid taking this medication. Caution is required when taking this medication alongside anticoagulants due to an increased risk of bleeding. In case of overdose, symptoms such as nausea, vomiting, headache, and edema may occur, necessitating immediate emergency treatment. Thyroid function and blood status should be monitored periodically during the usage of this medication, and if abnormal symptoms occur, prompt action should be taken.

Side effects

Agranulocytosis, leukopenia, hypoprothrombinemia, factor VII deficiency, thrombocytopenia, thrombocytopenic purpura, aplastic anemia, liver dysfunction, cholestatic hepatitis, jaundice, hair loss, skin pigmentation, itching, erythema, nausea, vomiting, diarrhea, anorexia, upper abdominal pain, acute pancreatitis, headache, dizziness, peripheral neuropathy, lethargy, drowsiness, rash, hives, fever, goiter, hypothyroidism, hepatitis, exfoliative dermatitis, neuritis, stimulation or inhibition of the central nervous system, periarteritis, lupus syndrome, hypoglycemic coma, lymphadenopathy, arthralgia, myalgia, salivary gland enlargement, edema, drug fever, sensory disturbances, loss of taste, nephritis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a container that blocks light. Additionally, it is best to store the medication at room temperature between 1°C and 30°C. Storing it this way helps maintain the medication's efficacy over time.

Appearance and packaging

Appearance

Green round tablets

Package unit

100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.