Methimazole 5 mg Tablets (Methimazole)

Adult dosage

Adults: The initial daily dose of methimazole is 15mg for mild cases, 30-40mg for moderate cases, and 60mg for severe cases, administered orally in 3 divided doses at 8-hour intervals. As hyperthyroidism resolves, the maintenance dose is 5-15mg per day in 1-2 divided doses.

Children's dosage

Children: The initial daily dose of this medicine is 0.4mg/kg of body weight, administered in 3 divided doses at 8-hour intervals. As hyperthyroidism resolves, the maintenance dose is 1/2 of the initial dose.

This drug should not be used by patients with serious blood disorders such as agranulocytosis, leukopenia, and thrombocytopenia. Patients who have had allergic reactions to this medication or are breastfeeding should avoid taking it. Patients who have experienced acute pancreatitis after taking this drug or similar medications in the past should also avoid it. Additionally, patients with lactose intolerance or certain genetic lactose metabolism disorders should not take this drug due to the lactose component it contains. Caution is advised for those with liver function issues, pregnant women or those with a possible pregnancy, and patients with other blood diseases. Regular blood tests should be conducted during treatment to monitor for blood abnormalities such as agranulocytosis or aplastic anemia. If liver dysfunction occurs, immediate testing should be undertaken, and the medication should be discontinued if necessary. Side effects such as skin rash, itching, headache, dizziness, and dyspepsia may occur, and if these symptoms persist, a consultation with a physician is advised. Serious side effects could occur in case of overdose, hence the prescribed dosage and amount must be strictly adhered to. During pregnancy, this medication may affect the fetus; therefore, women of childbearing potential should ensure effective contraception during treatment. In cases of use during pregnancy, the minimal effective dose should be administered, and close monitoring of the fetus and newborn is recommended. As this drug can be transmitted through breast milk affecting infants, breastfeeding women should not take it. When taken alongside anticoagulants, the risk of bleeding may increase; therefore, it is necessary to inform the physician and exercise caution. If symptoms such as sore throat, fever, or skin rash occur during the course of medication, immediate communication with healthcare providers is essential, and if symptoms indicating liver dysfunction or blood abnormalities arise, the use of the medication should be suspended and appropriate testing conducted.

Agranulocytosis, leukopenia, hypoprothrombinemia, factor VII deficiency, thrombocytopenia, thrombocytopenic purpura, aplastic anemia, liver dysfunction, cholestatic hepatitis, jaundice, hair loss, skin pigmentation, itching, erythema, nausea, vomiting, diarrhea, loss of appetite, upper abdominal pain, acute pancreatitis, headache, dizziness, peripheral neuropathy, fatigue, drowsiness, rash, urticaria, fever, goiter, hypothyroidism, hepatitis, exfoliative dermatitis, neuritis, stimulation or inhibition of the central nervous system, perivascular inflammation, lupus syndrome, hypoglycemic coma, lymphadenopathy, arthralgia, myalgia, salivary gland enlargement, edema, drug fever, sensory disturbances, loss of taste, nephritis

This drug is sensitive to light and should be stored in a container that does not allow light to enter. Additionally, it is best to store it at room temperature between 1 degree and 30 degrees Celsius. Proper storage will ensure the medication's effectiveness is safely maintained.

Appearance

White circular tablet

Package unit

100 tablets/bottle, 200 tablets/bottle