Medication info
Vforzial Tablet 5/80/10 Milligrams

Vforzial Tablet 5/80/10 Milligrams

Prescription medicationTablet경구
Ingredient · strength
Amlodipine Besylate›6.94mg / 1 tabletValsartan›80mg / 1 tabletRosuvastatin Calcium›10.4mg / 1 tablet
Manufacturer / importer
대웅바이오(주)
Appearance
Pink oval film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 202106224 · Approved 2021.08.27 · Insurance code 694003610

Summary

Main use
(Hypertension, dyslipidemia) improvement and cardiovascular disease risk reduction
Who takes it
Adults
Adult dose
This medication should be taken once a day with water. It is recommended to take it at the same time every day (e.g., before breakfast). For the Amlodipine/Valsartan combination, dosages of 5/80 milligrams, 5/160 milligrams, and 10/160 milligrams are available and should be individualized based on blood pressure control. Rosuvastatin is initiated at a dose of 5 milligrams once daily, with an increase to 10 milligrams as needed.

Ingredients

Manufacturer
대웅바이오(주)

Efficacy & effects

(Hypertension, dyslipidemia) improvement and cardiovascular disease risk reduction

  • Essential hypertension
  • primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • combined dyslipidemia
  • homozygous familial hypercholesterolemia
  • hypercholesterolemia
  • primary dysbetalipoproteinemia
  • elevated high-sensitivity C-reactive protein
  • hypertension
  • low HDL-cholesterol
  • smoking
  • family history of early coronary heart disease
View approved original text

This medication is used in patients who require a combination of Amlodipine and Valsartan, specifically for patients with essential hypertension whose blood pressure is not adequately controlled with monotherapy. Amlodipine dilates blood vessels to lower blood pressure, while Valsartan regulates blood pressure. Additionally, Rosuvastatin improves hypercholesterolemia and dyslipidemia, supporting vascular health and is used as an adjunct when dietary control is insufficient. This medication contributes to delaying the progression of atherosclerosis and reducing the risk of cardiovascular disease, stroke, and myocardial infarction. Therefore, it is used to manage both blood pressure and cholesterol levels together to reduce cardiovascular disease risk.

How to take

Adult dose

This medication should be taken once a day with water. It is recommended to take it at the same time every day (e.g., before breakfast). For the Amlodipine/Valsartan combination, dosages of 5/80 milligrams, 5/160 milligrams, and 10/160 milligrams are available and should be individualized based on blood pressure control. Rosuvastatin is initiated at a dose of 5 milligrams once daily, with an increase to 10 milligrams as needed.

Precautions

This medication can cause serious harm to a fetus, especially in the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. Patients with an allergy to any component of this medication, severely impaired liver or kidney function, or those who are pregnant or breastfeeding should not take this medicine. Patients with low sodium or fluid levels in the body should stabilize their condition before taking this medication, and if hypotensive symptoms appear during treatment, they should lie down and seek medical attention if necessary. Patients with elevated potassium levels or those taking other medications that can increase potassium should have their potassium levels monitored regularly, and patients with impaired kidney function should exercise caution. Particularly, patients who have undergone kidney transplants or have a history of angioedema, or those with severe heart failure or after myocardial infarction should use this medication cautiously and have their blood pressure and kidney function checked frequently. This medication can cause muscle pain, muscle weakness, and in rare cases, severe muscle damage known as rhabdomyolysis, so immediate consultation with a doctor is advised if any unusual muscle symptoms occur. Elderly patients may be more sensitive to this medication, so starting with a lower dose and titrating slowly is advisable. Dizziness or fatigue may occur while driving or operating machinery, so caution is required. This medication may interact with other drugs, so if other medications are currently being taken, it is essential to inform the doctor or pharmacist. Pregnant or breastfeeding women should not take this medication; those planning to become pregnant should consult a doctor. Safety and efficacy in pediatric or adolescent patients has not been established, and its use is not recommended.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), tightness in the chest, angioedema, hypersensitivity reactions including angioedema, Stevens-Johnson syndrome, toxic epidermal necrolysis, severe allergic reactions, severe skin reactions, jaundice, liver issues (jaundice), sudden and severe headaches, seizures, confusion, vision changes, paralysis, severe neurological symptoms, urination

Mild side effects

  • Peripheral edema
  • warmth sensation
  • ALT increase
  • AST increase
  • elevated blood creatinine
  • flank pain
  • sore throat
  • dizziness
  • sensory loss
  • nasopharyngitis
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  • rash
  • nasopharyngitis
  • influenza
  • anxiety
  • drowsiness
  • orthostatic dizziness
  • vertigo
  • tinnitus
  • tachycardia
  • palpitations
  • syncope
  • orthostatic hypotension
  • hypotension
  • cough
  • pharyngeal and laryngeal pain
  • diarrhea
  • nausea
  • abdominal pain
  • constipation
  • dry mouth
  • erythema
  • sweating
  • itching
  • joint swelling

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. Additionally, it is best to store it at room temperature between 1 to 30 degrees Celsius, away from extreme heat or cold conditions.

Appearance and packaging

Appearance

Pink oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.