Medication info
Ensium Tablet 500 mg (Dorbeshil Acid Calcium Hydrate)

Ensium Tablet 500 mg (Dorbeshil Acid Calcium Hydrate)

Prescription medicationTabletOral
Ingredient · strength
Dobesilate Calcium Hydrate›500mg / 1 tablet
Manufacturer / importer
Hanlim Pharmaceutical Co., Ltd.
Appearance
White rectangular tablet
Packaging
30 tablets/bottle, 90 tablets/bottle
Approval status
Active

MFDS item code 202106213 · Approved 2021.08.27 · Insurance code 645306600

Summary

Main use
Treatment of microvascular disorders (e.g., diabetic retinopathy), venous disorders (e.g., edema), and hemorrhoids
Who takes it
Adults
Adult dose
Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular disorders and retinopathy: 500~1000mg daily 2. Venous disorders: 750mg daily for 1~3 weeks, followed by 500mg daily. Take after meals with plenty of fluids. The dose may be adjusted according to age and symptoms.

Ingredients

Manufacturer
Hanlim Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of microvascular disorders (e.g., diabetic retinopathy), venous disorders (e.g., edema), and hemorrhoids

  • Excessive capillary ruptures
  • permeability disorders
  • vascular damage
  • diabetic microangiopathy
  • diabetic retinopathy
  • venous insufficiency
  • post-thrombotic syndrome
  • peripheral venous edema
  • hemorrhoids
View approved original text

This medication is effectively used for various symptoms and diseases involving damage and dysfunction of capillaries, such as microvascular disorders and retinopathy due to diabetes, venous insufficiency, post-thrombotic syndrome, peripheral venous edema, and hemorrhoids. It is used to alleviate symptoms and assist in blood circulation by improving these vascular-related issues.

How to take

Adult dose

Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular disorders and retinopathy: 500~1000mg daily 2. Venous disorders: 750mg daily for 1~3 weeks, followed by 500mg daily. Take after meals with plenty of fluids. The dose may be adjusted according to age and symptoms.

Precautions

This medication contains Dorbeshil Acid Calcium Hydrate as the active ingredient and should be avoided in certain patients. First, patients who have allergic reactions or hypersensitivity to any of the ingredients in this medication, as well as pregnant or breastfeeding women, should not take this medication. Additionally, patients with a genetic intolerance to galactose, lactose deficiency, or glucose-galactose malabsorption should not use this medication. Patients with impaired renal function need to be cautious as this medication is excreted through the kidneys, and especially in cases of severe renal failure requiring dialysis, dosage adjustments may be necessary. Patients with compromised liver function should also use this medication with caution, and if liver enzyme levels rise, treatment should be re-evaluated. This medication includes sodium metabisulfite, which can cause allergic reactions or severe asthma attacks in individuals sensitive to sulfites, particularly in asthma patients. Possible side effects of this medication include headache, abdominal pain, nausea, diarrhea, vomiting, arthralgia, myalgia, elevated liver enzyme levels, and rarely allergic symptoms such as skin rash, itching, and hives. Additionally, a very rare but serious blood disorder called agranulocytosis may occur, and if high fever or symptoms of infection appear, the doctor should be notified immediately, and this medication should be discontinued. In case of severe hypersensitivity reactions, medication administration should be stopped immediately and medical assistance should be sought. No special interactions with other medications are known; however, this medication can affect blood test results, so it is advisable to undergo blood tests before taking it.

Side effects

  • Agranulocytosis
  • neutropenia
  • leukopenia
  • skin rash
  • allergic dermatitis
  • pruritus
  • urticaria
  • facial edema
  • anaphylactic reaction
  • headache
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  • abdominal pain
  • nausea
  • diarrhea
  • vomiting
  • increased alanine aminotransferase
  • arthralgia
  • myalgia
  • fever
  • chills
  • lethargy
  • fatigue

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a container that does not allow light to enter. Additionally, it is best to keep it at room temperature between 1 degree and 30 degrees.

Appearance and packaging

Appearance

White rectangular tablet

Package unit

30 tablets/bottle, 90 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.