Dobian ES 500 mg (Dosesil Calcium Hydrate)

Adult dose

Adults: Administer the following doses orally as calcium dobesilate monohydrate. 1. Vascular damage and retinopathy: 500 ~ 1000mg daily 2. Venous disease: Administer 750mg daily for 1 ~ 3 weeks, then administer 500mg daily. Take after meals with plenty of fluids. Adjust the dose as appropriate according to age and symptoms.

This medication is primarily composed of Dosesil Calcium Hydrate and should not be used in certain patients. Patients who are allergic to this medicine or its components should not take it. Pregnant or breastfeeding women should also avoid using this medication. Furthermore, as it contains lactose, patients with lactose intolerance or certain genetic issues should refrain from taking this medication. Caution is required for patients with impaired kidney function. Since this medication is primarily excreted in urine, dosage adjustment may be necessary for patients with severely reduced kidney function. Patients with liver impairment should also use this medication cautiously, and treatment should be reevaluated if liver enzyme levels become elevated. This medication contains sulfites, which may cause severe allergic reactions or asthma attacks in people allergic to sulfites or asthmatics, so caution is warranted. Common side effects may include headache, abdominal pain, nausea, diarrhea, vomiting, elevated liver function tests, arthralgia, myalgia, fever, chills, lethargy, and fatigue. Rarely, serious side effects affecting blood cell counts may occur, thus immediate consultation with a doctor is advised if symptoms such as high fever or signs of infection arise. If symptoms of allergy such as skin rash, itching, or facial swelling occur, discontinue use immediately and inform a doctor. Prior to taking this medication, it is advisable to undergo laboratory tests such as blood tests to minimize interactions with the test results.

• Agranulocytosis
• neutropenia
• leukopenia
• hypersensitivity reactions
• skin rash
• allergic dermatitis
• pruritus
• urticaria
• facial edema
• anaphylactic reaction

This medication is sensitive to light, so it should be stored in a dark place and kept in a tightly sealed container that does not allow air to enter. Maintaining a storage temperature between 1 and 30 degrees Celsius is important.

Appearance

White rectangular tablet

Package unit

30 tablets/bottle, 60 tablets/bottle, 90 tablets/bottle