Rivarozet 4/10 mg Tablets

Adult dose

This medication is taken once daily without regard to meals. The recommended initial dose is 2/10 mg once daily. If the LDL-cholesterol lowering effect is insufficient, the dose may be increased up to a maximum of 4/10 mg once daily. Dosing adjustments should be made based on the patient's response at intervals of 4 weeks or more. For patients taking pitavastatin calcium and ezetimibe simultaneously, this medication (a combination product with the same content of active ingredients) can be converted for convenience. For patients with liver impairment, an initial dose of 1 mg once daily is recommended, with the maximum dose being 2/10 mg once daily.

This medication should not be used in certain patients. For example, it should not be administered to patients with allergies to its components, those with severe liver disease, pregnant women, nursing mothers, or children. Patients with impaired liver function or those who consume alcohol excessively should use this medication with caution. Additionally, patients with kidney problems or a history of myopathy should be administered this drug carefully. If symptoms such as muscle pain or weakness appear while taking this medication, immediate consultation with a physician is necessary as these may indicate serious side effects such as muscle damage or rhabdomyolysis. Regular liver function tests should be conducted, and if liver enzyme levels are abnormally elevated, discontinuation of the medication may be required. This medication should not be administered to pregnant women or women of childbearing potential, and should be discontinued immediately if taken during pregnancy. Caution should be taken when this medication is combined with other drugs due to potential interactions, especially with cyclosporine, fibrate medications, and niacin. Elderly individuals may experience adverse reactions, so caution is needed when administering this medication to them. In the case of overdose, since there is no specific antidote, treatment should be symptomatic and monitoring of liver function and muscle status should be conducted. Finally, this medication should be kept out of the reach of children and should not be transferred to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, dyspnea or difficulty breathing, asthma attack, respiratory abnormalities accompanied by coughing and fever, jaundice (yellowing of skin or eyes), profound lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

Headache, dizziness, constipation, abdominal pain, dyspepsia, nausea, upper respiratory tract infection, nasopharyngitis, pruritus, muscle spasm, fatigue, diarrhea, malaise, itching, rash, hypertension, palpitations, weakness, dry mouth, loss of appetite, stomatitis, glossitis, belching, gastrointestinal disturbance, discomfort in the epigastrium, increased blood creatinine, decreased platelet count, increased blood urea, elevated serum potassium and phosphorus levels, dysgeusia, discoloration of urine, hair loss, sleep disturbances, memory loss,

This medication is sensitive to light and should be stored in a container that blocks light. Additionally, it is important to maintain the drug’s efficacy by storing it at room temperature, between 1 to 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)], 100 tablets/bottle